Literature DB >> 639961

Inhibition of testicular androgenesis by urinary gonadotropin-inhibiting substances in rats.

M Ota, N Sato, K Obara.   

Abstract

The effect of urinary gonadotropin-inhibiting substances (GIS) on the androgen synthesis in rat testes was studied in vitro and in vivo. GIS, which was added to the incubation medium containing tesased testicular tissues and injected into rats for 2 days, showed a suppressive effect on the formation of androstenedione from pregnenolone in the testis.

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Year:  1978        PMID： 639961     DOI： 10.1007/BF01935979

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  16 in total

1.  Metabolism in vitro of (4-14C) testosterone by liver homogenates of normal and carbon tetrachloride injured rats.

Authors:  N Sato; M Ota; K Obara
Journal:  Tohoku J Exp Med       Date:  1969-07       Impact factor: 1.848

2.  A melatonin-free extract of bovine pineal with antigonadotropic activity.

Authors:  B Benson; M J Matthews; A E Rodin
Journal:  Life Sci I       Date:  1971-06-01

3.  Sex differences in metabolism of testosterone by rat liver.

Authors:  M Ota; N Sato; K Obara
Journal:  J Biochem       Date:  1972-07       Impact factor: 3.387

4.  Gonadotrophin-inhibiting substance in bovine urine.

Authors:  N Ayalon; B Landau; I Lewis
Journal:  Int J Fertil       Date:  1970 Jan-Mar

5.  Effect of urinary gonadotrophin-inhibiting substance on endogenous and exogenous ovulatory gonadotrophins in the mouse.

Authors:  M Ota; A H Gates; A Dronkert
Journal:  J Endocrinol       Date:  1970-09       Impact factor: 4.286

6.  Presence of a gonadotropin inhibiting substance in the urine of albino rats.

Authors:  M Ota; K S Hsieh; K Obara
Journal:  Endocrinol Jpn       Date:  1970-10

7.  Testicular steroidogeneis in vitro in the rat in response to blinding, pinealectomy and to the addition of melatonin.

Authors:  F Peat; G A Kinson
Journal:  Steroids       Date:  1971-02       Impact factor: 2.668

8.  Absence of gonadotropin-inhibiting substance in the urine of pinealectomized rats.

Authors:  M Ota; K S Hsieh; K Obara
Journal:  Endocrinology       Date:  1971-04       Impact factor: 4.736

9.  [Recent advances on the antigonadotropic factor of the pineal gland (author's transl)].

Authors:  L Thieblot; M Menigot
Journal:  J Neurovisc Relat       Date:  1971

10.  Melatonin, a pineal substance: effect on the rat ovary.

Authors:  R J WURTMAN; J AXELROD; E W CHU
Journal:  Science       Date:  1963-07-19       Impact factor: 47.728
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