| Literature DB >> 639934 |
P Kumar, J P Nagpaul, B Singh, R C Bansal, R Sharma.
Abstract
Isatin has been found to inhibit rat testicular alkaline phosphatase (EC 3.1.3.1). That the inhibition is non-competitive as well as non-allosteric is evident from a) the hyperbolic curve relating inhibition as a function of inhibitor concentration; b) the small change in enthalpy, free energy and entropy; c) the number of isatin molecules associating with 1 molecule of the enzyme (n=1.29); and, d) the decrease in the values of both Km and Vmax in the presence of isatin.Entities:
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Year: 1978 PMID： 639934 DOI： 10.1007/BF01935909
Source DB: PubMed Journal: Experientia ISSN： 0014-4754