Literature DB >> 6399233

Acanthamoeba keratitis successfully treated with penetrating keratoplasty: suggested immunogenic mechanisms of action.

H J Blackman, N A Rao, M A Lemp, G S Visvesvara.   

Abstract

A patient with a corneal ulcer caused by Acanthamoeba polyphaga has been successfully treated with a penetrating keratoplasty. The pathologic specimen showed no inflammatory infiltrate surrounding the intact amoeba, whereas necrotic organisms were surrounded by an intense cellular reaction. Indirect immunochemical studies showed that the trophozoite stained profusely, but the cyst form exhibited the antigenic site on the cyst wall.

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Year:  1984        PMID: 6399233

Source DB:  PubMed          Journal:  Cornea        ISSN: 0277-3740            Impact factor:   2.651


  5 in total

1.  Experimental Acanthamoeba keratitis: I. Preliminary findings.

Authors:  D F Larkin; D L Easty
Journal:  Br J Ophthalmol       Date:  1990-09       Impact factor: 4.638

2.  Persistence of acanthamoeba antigen following acanthamoeba keratitis.

Authors:  Y F Yang; M Matheson; J K Dart; I A Cree
Journal:  Br J Ophthalmol       Date:  2001-03       Impact factor: 4.638

3.  Characterisation and differentiation of pathogenic and non-pathogenic Acanthamoeba strains by their protein and antigen profiles.

Authors:  J Walochnik; K Sommer; A Obwaller; E-M Haller-Schober; H Aspöck
Journal:  Parasitol Res       Date:  2004-01-13       Impact factor: 2.289

Review 4.  An update on Acanthamoeba keratitis: diagnosis, pathogenesis and treatment.

Authors:  Jacob Lorenzo-Morales; Naveed A Khan; Julia Walochnik
Journal:  Parasite       Date:  2015-02-18       Impact factor: 3.000

Review 5.  Non-contact lens related Acanthamoeba keratitis.

Authors:  Prashant Garg; Paavan Kalra; Joveeta Joseph
Journal:  Indian J Ophthalmol       Date:  2017-11       Impact factor: 1.848

  5 in total

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