Literature DB >> 639477

Circadian rhythmicity of delayed hypersensitivity to oxazolone in the rat.

R Pownall, M S Knapp.   

Abstract

1. A marked circadian rhythm was detected in the ear swelling of rats immunized and then challenged with oxazolone. 2. The peak response observed at 10.00 hours was over eight times the minimum at 16.00 hours. 3. As related tests are used frequently in man greater attention to clock time is necessary in clinical immunology.

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Year:  1978        PMID： 639477     DOI： 10.1042/cs0540447

Source DB:  PubMed          Journal:  Clin Sci Mol Med        ISSN： 0301-0538


  6 in total

1.  Possible effect of time on renal allograft rejection.

Authors:  M S Knapp; J R Cove-Smith; R Dugdale; N Mackenzie; R Pownall
Journal:  Br Med J       Date:  1979-01-13

2.  Lymphocytes are rhythmic: is this important?

Authors:  M S Knapp; R Pownall
Journal:  Br Med J (Clin Res Ed)       Date:  1984-11-17

3.  The effects of corticosteroids given at various clock times on cell-mediated immunity to oxazolone [proceedings].

Authors:  T A Kabler; M S Knapp; R Pownall; T Bennett
Journal:  Br J Pharmacol       Date:  1978-11       Impact factor: 8.739

4.  Time of day of taking immunosuppressive agents after renal transplantation: a possible influence on graft survival.

Authors:  M S Knapp; N P Byrom; R Pownall; P Mayor
Journal:  Br Med J       Date:  1980-11-22

5.  Circadian variations in the signs and symptoms of rheumatoid arthritis and in the therapeutic effectiveness of flurbiprofen at different times of day.

Authors:  I C Kowanko; R Pownall; M S Knapp; A J Swannell; P G Mahoney
Journal:  Br J Clin Pharmacol       Date:  1981-05       Impact factor: 4.335

6.  The time of day of antigen encounter influences the magnitude of the immune response.

Authors:  R Pownall; P A Kabler; M S Knapp
Journal:  Clin Exp Immunol       Date:  1979-05       Impact factor: 4.330
  6 in total

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