A calcium-binding protein is a regulatory subunit of quinate:NAD+ oxidoreductase from dark-grown carrot cells.

On transfer of carrot cell-suspensions from light to dark conditions, quinate:NAD+ oxidoreductase binds, post-translationally, an additional subunit. As a consequence, the oligomeric enzyme becomes activatable by Ca++ and behaves as a Ca++ binding protein. The additional subunit has been shown to be the Ca++ binding moiety of the molecule that protects the phosphorylated amino acids from dephosphorylation. It is suggested that the regulatory subunit may be a new class of calciprotein.