Literature DB >> 6392567

Genetic studies of the lac repressor. XII. Amino acid replacements in the DNA binding domain of the Escherichia coli lac repressor.

J H Miller.   

Abstract

Out of the first 62 residues of the lac repressor, 38 positions have been substituted by at least one amino acid exchange. The total number of replacements in this region is 131. Data from several studies are considered.

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Year:  1984        PMID: 6392567     DOI: 10.1016/0022-2836(84)90438-8

Source DB:  PubMed          Journal:  J Mol Biol        ISSN: 0022-2836            Impact factor:   5.469


  10 in total

1.  Spontaneous mutation in the Escherichia coli lacI gene.

Authors:  R M Schaaper; R L Dunn
Journal:  Genetics       Date:  1991-10       Impact factor: 4.562

2.  lac repressor: crystallization of intact tetramer and its complexes with inducer and operator DNA.

Authors:  H C Pace; P Lu; M Lewis
Journal:  Proc Natl Acad Sci U S A       Date:  1990-03       Impact factor: 11.205

3.  Insertion mutagenesis of the lac repressor and its implications for structure-function analysis.

Authors:  B D Nelson; C Manoil; B Traxler
Journal:  J Bacteriol       Date:  1997-06       Impact factor: 3.490

4.  Dominant negative mutations in the Tn10 tet repressor: evidence for use of the conserved helix-turn-helix motif in DNA binding.

Authors:  P J Isackson; K P Bertrand
Journal:  Proc Natl Acad Sci U S A       Date:  1985-09       Impact factor: 11.205

5.  Spectra of spontaneous mutations in Escherichia coli strains defective in mismatch correction: the nature of in vivo DNA replication errors.

Authors:  R M Schaaper; R L Dunn
Journal:  Proc Natl Acad Sci U S A       Date:  1987-09       Impact factor: 11.205

6.  DNA sequence analysis of mutagenicity and site specificity of ethyl methanesulfonate in Uvr+ and UvrB- strains of Escherichia coli.

Authors:  P A Burns; F L Allen; B W Glickman
Journal:  Genetics       Date:  1986-08       Impact factor: 4.562

7.  Characterization of mutational specificity within the lacI gene for a mutD5 mutator strain of Escherichia coli defective in 3'----5' exonuclease (proofreading) activity.

Authors:  R G Fowler; R M Schaaper; B W Glickman
Journal:  J Bacteriol       Date:  1986-07       Impact factor: 3.490

8.  Evidence for a contact between glutamine-18 of lac repressor and base pair 7 of lac operator.

Authors:  R H Ebright
Journal:  Proc Natl Acad Sci U S A       Date:  1986-01       Impact factor: 11.205

9.  AlloRep: A Repository of Sequence, Structural and Mutagenesis Data for the LacI/GalR Transcription Regulators.

Authors:  Filipa L Sousa; Daniel J Parente; David L Shis; Jacob A Hessman; Allen Chazelle; Matthew R Bennett; Sarah A Teichmann; Liskin Swint-Kruse
Journal:  J Mol Biol       Date:  2015-09-25       Impact factor: 5.469

10.  Data on publications, structural analyses, and queries used to build and utilize the AlloRep database.

Authors:  Filipa L Sousa; Daniel J Parente; Jacob A Hessman; Allen Chazelle; Sarah A Teichmann; Liskin Swint-Kruse
Journal:  Data Brief       Date:  2016-07-09
  10 in total

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