Literature DB >> 6390739

Functional testing and chemical composition of cryptococcal extracts.

N K Hall, K C Maluf, R Blackstock.   

Abstract

Three antigens were compared for their ability to detect immune responses in C57Bl/6 mice sensitized to Cryptococcus neoformans. Elicitation of responses in vitro was greatest with a urea extract antigen, followed in efficiency by an alkali extract and a soluble capsular polysaccharide preparation. The reactivity paralleled the protein content of the preparation.

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Year:  1984        PMID： 6390739     DOI： 10.1080/00362178485380701

Source DB:  PubMed          Journal:  Sabouraudia        ISSN： 0036-2174


  2 in total

1.  Presentation of cryptococcal capsular polysaccharide (GXM) on activated antigen-presenting cells inhibits the T-suppressor response and enhances delayed-type hypersensitivity and survival.

Authors:  R Blackstock; A Casadevall
Journal:  Immunology       Date:  1997-11       Impact factor: 7.397

2.  T cell-mediated immunity in the lung: a Cryptococcus neoformans pulmonary infection model using SCID and athymic nude mice.

Authors:  G B Huffnagle; J L Yates; M F Lipscomb
Journal:  Infect Immun       Date:  1991-04       Impact factor: 3.441
  2 in total

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