| Literature DB >> 6390045 |
R P Abergel, R M Dwyer, C A Meeker, G Lask, A P Kelly, J Uitto.
Abstract
Biochemical studies utilizing keloid fibroblast cultures revealed that Nd:YAG laser selectively suppressed collagen production by these cells. Based on these in vitro observations, eight patients with keloids were treated with Nd:YAG laser in a nondestructive manner. Results, with a 3-year follow-up, indicated flattening and softening of the lesions. Thus, the results suggest that Nd:YAG laser is an effective treatment modality for keloids, and its mechanism may involve bioinhibition of fibroblast functions.Entities:
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Year: 1984 PMID: 6390045 DOI: 10.1002/lsm.1900040310
Source DB: PubMed Journal: Lasers Surg Med ISSN: 0196-8092 Impact factor: 4.025