Literature DB >> 6389815

Aspirin in acute gastroenteritis: a clinical and microbiological study.

M Gracey, M A Phadke, V Burke, S K Raut, B Singh.   

Abstract

Soluble aspirin given by mouth in divided dosage decreased intestinal fluid loss in infants and young children with acute gastroenteritis. The treated group had significantly less diarrhea, which ceased earlier and needed less intravenous therapy, than a randomly selected control group given an indistinguishable placebo. This effect of aspirin occurred with diarrhea caused by Salmonella, Aeromonas, Escherichia coli producing heat-labile toxin, and rotavirus, but not with diarrhea associated with strains of E. coli producing heat-stable toxin.

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Year:  1984        PMID： 6389815     DOI： 10.1097/00005176-198411000-00009

Source DB:  PubMed          Journal:  J Pediatr Gastroenterol Nutr        ISSN： 0277-2116            Impact factor:   2.839


  6 in total

Review 1.  Pharmacoeconomics of the therapy of diarrhoeal disease.

Authors:  K A Nathavitharana; I W Booth
Journal:  Pharmacoeconomics       Date:  1992-10       Impact factor: 4.981

2.  Role of intestinal epithelial cells in the host secretory response to infection by invasive bacteria. Bacterial entry induces epithelial prostaglandin h synthase-2 expression and prostaglandin E2 and F2alpha production.

Authors:  L Eckmann; W F Stenson; T C Savidge; D C Lowe; K E Barrett; J Fierer; J R Smith; M F Kagnoff
Journal:  J Clin Invest       Date:  1997-07-15       Impact factor: 14.808

3.  Inhibition of cyclooxygenase activity reduces rotavirus infection at a postbinding step.

Authors:  John W A Rossen; Janneke Bouma; Rolien H C Raatgeep; Hans A Büller; Alexandra W C Einerhand
Journal:  J Virol       Date:  2004-09       Impact factor: 5.103

Review 4.  Aspirin and Infection: A Narrative Review.

Authors:  Stefano Di Bella; Roberto Luzzati; Luigi Principe; Verena Zerbato; Elisa Meroni; Mauro Giuffrè; Lory Saveria Crocè; Marco Merlo; Maria Perotto; Elisabetta Dolso; Cristina Maurel; Antonio Lovecchio; Eugenia Dal Bo; Cristina Lagatolla; Bruna Marini; Rudy Ippodrino; Gianfranco Sanson
Journal:  Biomedicines       Date:  2022-01-25

Review 5.  Therapeutics and Immunoprophylaxis Against Noroviruses and Rotaviruses: The Past, Present, and Future.

Authors:  Souvik Ghosh; Yashpal Singh Malik; Nobumichi Kobayashi
Journal:  Curr Drug Metab       Date:  2018       Impact factor: 3.731

Review 6.  Mechanisms of diarrhoea.

Authors:  I W Booth; A S McNeish
Journal:  Baillieres Clin Gastroenterol       Date:  1993-06
  6 in total

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