Literature DB >> 6389592

Rabbit antiserum to a citric acid extract of human skeletal muscle staining thymomas from myasthenia gravis patients.

N E Gilhus, J A Aarli, B Christensson, R Matre.   

Abstract

Rabbit antiserum to a citric acid extract of human skeletal muscle (CA) stained both the cell membrane and the cross-striational bands of skeletal muscle cells. The rabbit antiserum also stained the cell membrane of epithelial thymoma cells from myasthenia gravis (MG) patients. Normal and hyperplastic thymus tissue were not stained, apart from scattered myoid thymic cells. Absorption of the antiserum with CA abolished staining of the thymoma, indicating that human skeletal muscle and epithelial thymoma cells possess common antigens.

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Year:  1984        PMID： 6389592     DOI： 10.1016/s0165-5728(84)80006-5

Source DB:  PubMed          Journal:  J Neuroimmunol        ISSN： 0165-5728            Impact factor:   3.478


  8 in total

1.  Pathogenesis of myasthenia gravis. Acetylcholine receptor-related antigenic determinants in tumor-free thymuses and thymic epithelial tumors.

Authors:  T Kirchner; S Tzartos; F Hoppe; B Schalke; H Wekerle; H K Müller-Hermelink
Journal:  Am J Pathol       Date:  1988-02       Impact factor: 4.307

2.  A pathogenetic role for the thymoma in myasthenia gravis. Autosensitization of IL-4- producing T cell clones recognizing extracellular acetylcholine receptor epitopes presented by minority class II isotypes.

Authors:  N Nagvekar; A M Moody; P Moss; I Roxanis; J Curnow; D Beeson; N Pantic; J Newsom-Davis; A Vincent; N Willcox
Journal:  J Clin Invest       Date:  1998-05-15       Impact factor: 14.808

3.  Proteins with epitopes of the acetylcholine receptor in epithelial cell cultures of thymomas in myasthenia gravis.

Authors:  A Marx; T Kirchner; F Hoppe; R O'Connor; B Schalke; S Tzartos; H K Müller-Hermelink
Journal:  Am J Pathol       Date:  1989-04       Impact factor: 4.307

4.  Patients with myasthenia gravis and thymoma have in their sera IgG autoantibodies against titin.

Authors:  J A Aarli; K Stefansson; L S Marton; R L Wollmann
Journal:  Clin Exp Immunol       Date:  1990-11       Impact factor: 4.330

5.  Expression of neurofilaments and of a titin epitope in thymic epithelial tumors. Implications for the pathogenesis of myasthenia gravis.

Authors:  A Marx; A Wilisch; A Schultz; A Greiner; B Magi; V Pallini; B Schalke; K Toyka; W Nix; T Kirchner; H K Müller-Hermelink
Journal:  Am J Pathol       Date:  1996-06       Impact factor: 4.307

6.  Myasthenic and nonmyasthenic thymoma. An expansion of a minor cortical epithelial cell subset?

Authors:  N Willcox; M Schluep; M A Ritter; H J Schuurman; J Newsom-Davis; B Christensson
Journal:  Am J Pathol       Date:  1987-06       Impact factor: 4.307

7.  Thymomatous epithelial cells and skeletal muscle share a common epitope defined by a monoclonal antibody.

Authors:  M Dardenne; W Savino; J F Bach
Journal:  Am J Pathol       Date:  1987-01       Impact factor: 4.307

8.  Oncogene proteins and proliferation antigens in thymomas: increased expression of epidermal growth factor receptor and Ki67 antigen.

Authors:  N E Gilhus; M Jones; H Turley; K C Gatter; N Nagvekar; J Newsom-Davis; N Willcox
Journal:  J Clin Pathol       Date:  1995-05       Impact factor: 3.411
  8 in total

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