Literature DB >> 6389500

Overproduction of tryptophanyl-tRNA synthetase relieves transcription termination at the Escherichia coli tryptophan operon attenuator.

A Das, C Yanofsky.   

Abstract

Overproduction of tryptophanyl-tRNA synthetase increased trp operon expression by reducing transcription termination at the trp attenuator. The total cellular level of charged tRNATrp was not affected by increased levels of the synthetase. We propose that excess synthetase binds charged tRNATrp and reduces the concentration available for translation.

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Year:  1984        PMID: 6389500      PMCID: PMC214812          DOI: 10.1128/jb.160.2.805-807.1984

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  33 in total

1.  Regulation of the expression of the histidine operon in Salmonella typhimurium.

Authors:  T Kasai
Journal:  Nature       Date:  1974-06-07       Impact factor: 49.962

2.  Thr region between the operator and first structural gene of the tryptophan operon of Escherichia coli may have a regulatory function.

Authors:  E N Jackson; C Yanofsky
Journal:  J Mol Biol       Date:  1973-05-05       Impact factor: 5.469

3.  Transfer ribonucleic acid synthetase catalyzed deacylation of aminoacyl transfer ribonucleic acid in the absence of adenosine monophosphate and pyrophosphate.

Authors:  A A Schreier; P R Schimmel
Journal:  Biochemistry       Date:  1972-04-25       Impact factor: 3.162

4.  Tryptophanyl transfer ribonucleic acid synthetase of Escherichia coli. I. Purification of the enzyme and of tryptrophan transfer ribonucleic acid.

Authors:  D R Joseph; K H Muench
Journal:  J Biol Chem       Date:  1971-12-25       Impact factor: 5.157

5.  Purification and physical characterization of tyrosyl ribonucleic acid synthetases from Escherichia coli and Bacillus subtilis.

Authors:  R Calendar; P Berg
Journal:  Biochemistry       Date:  1966-05       Impact factor: 3.162

6.  Dual-control of the tryptophan operon is mediated by both tryptophanyl-tRNA synthetase and the repressor.

Authors:  D E Morse; A N Morse
Journal:  J Mol Biol       Date:  1976-05-15       Impact factor: 5.469

7.  Histidine regulation in Salmonella typhimurium. VII. Purification and general properties of the histidyl transfer ribonucleic acid synthetase.

Authors:  F De Lorenzo; B N Ames
Journal:  J Biol Chem       Date:  1970-04-10       Impact factor: 5.157

8.  Histidyl-transfer ribonucleic acid synthetase in positive control of the histidine operon in Salmonella typhimurium.

Authors:  J H Wyche; B Ely; T A Cebula; M C Snead; P E Hartman
Journal:  J Bacteriol       Date:  1974-02       Impact factor: 3.490

9.  Histidine regulation in Salmonella typhimurium. XI. The percentage of transfer RNA His charged in vivo and its relation to the repression of the histidine operon.

Authors:  J A Lewis; B N Ames
Journal:  J Mol Biol       Date:  1972-04-28       Impact factor: 5.469

10.  Characterization of altered forms of glycyl transfer ribonucleic acid synthetase and the effects of such alterations on aminoacyl transfer ribonucleic acid synthesis in vivo.

Authors:  W R Folk; P Berg
Journal:  J Bacteriol       Date:  1970-04       Impact factor: 3.490

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