| Literature DB >> 6389500 |
Abstract
Overproduction of tryptophanyl-tRNA synthetase increased trp operon expression by reducing transcription termination at the trp attenuator. The total cellular level of charged tRNATrp was not affected by increased levels of the synthetase. We propose that excess synthetase binds charged tRNATrp and reduces the concentration available for translation.Entities:
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Year: 1984 PMID: 6389500 PMCID: PMC214812 DOI: 10.1128/jb.160.2.805-807.1984
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490