Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Dysfibrinogenemia. A current perspective.

Literature DB >> 6388985

Dysfibrinogenemia. A current perspective.

Abstract

At least 24 single amino acid substitution dysfibrinogens are currently known. Emerging evidence supports conclusions reached from studies on normal fibrinogen, which relate to the importance of release of A peptides to formation of a physiologically adequate fibrin clot; the existence of "D-D" or (b-b) polymerization sites; and the importance of the gamma chain carboxy terminal segment in fibrin assembly.

Entities: Disease

Mesh：

Substances：
Fibrin
Fibrinogen

Year: 1984 PMID： 6388985

Source DB: PubMed Journal: Clin Lab Med ISSN： 0272-2712 Impact factor: 1.935

Keyword Cloud
Cited

2 in total

1. Fibrinogen Stony Brook, a heterozygous A alpha 16Arg----Cys dysfibrinogenemia. Evaluation of diminished platelet aggregation support and of enhanced inhibition of fibrin assembly.

Authors: D K Galanakis; A Henschen; E I Peerschke; M Kehl
Journal: J Clin Invest Date: 1989-07 Impact factor: 14.808

2. A novel mutation in exon 2 of FGB caused by c.221G>T ^† substitution, predicting the replacement of the native Arginine at position 74 with a Leucine (p.Arg74Leu ^† ) in a proband from a Kurdish family with dysfibrinogenaemia and familial venous and arterial thrombosis.

Authors: Abdul A Shlebak; Alexia D Katsarou; George Adams; Fiona Fernando
Journal: J Thromb Thrombolysis Date: 2017-02 Impact factor: 2.300

2 in total

Dysfibrinogenemia. A current perspective.

1. Fibrinogen Stony Brook, a heterozygous A alpha 16Arg----Cys dysfibrinogenemia. Evaluation of diminished platelet aggregation support and of enhanced inhibition of fibrin assembly.

2. A novel mutation in exon 2 of FGB caused by c.221G>T † substitution, predicting the replacement of the native Arginine at position 74 with a Leucine (p.Arg74Leu † ) in a proband from a Kurdish family with dysfibrinogenaemia and familial venous and arterial thrombosis.

2. A novel mutation in exon 2 of FGB caused by c.221G>T ^† substitution, predicting the replacement of the native Arginine at position 74 with a Leucine (p.Arg74Leu ^† ) in a proband from a Kurdish family with dysfibrinogenaemia and familial venous and arterial thrombosis.