Literature DB >> 6386756

The fine structure of HNK-1 (Leu7) positive cells. A study using an immunoperoxidase technique.

G C Manara, G de Panfilis, C Ferrari, A Bonati, R Scandroglio.   

Abstract

The ultrastructural characteristics of HNK-1 (Leu7) positive cells, visualized with a peroxidase labelled anti-mouse IgM serum, were analysed. Our investigation demonstrates: 1) the majority of Leu7 positive cells has a low nuclear/cytoplasmic ratio (N/C), an irregular outline, a well developed smooth endoplasmic reticulum, parallel tubular arrays (PTA) and electron dense granules; 2) the minority of Leu7 positive cells has a high N/C, regular profiles and lacks electron dense granules. The presence of two distinct ultrastructural patterns within Leu7 positive cells may represent: 1) the expression of subsequent stages of cell differentiation; 2) two distinct Leu7 positive cell subpopulations.

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Year:  1984        PMID： 6386756     DOI： 10.1007/bf00490109

Source DB:  PubMed          Journal:  Histochemistry        ISSN： 0301-5564


  27 in total

1.  Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

Authors:  A Böyum
Journal:  Scand J Clin Lab Invest Suppl       Date:  1968

2.  T gamma cells express T lymphocyte-associated antigens.

Authors:  R I Fox; L F Thompson; J R Huddlestone
Journal:  J Immunol       Date:  1981-05       Impact factor: 5.422

Review 3.  Correlation of functional properties of human lymphoid cell subsets and surface marker phenotypes using multiparameter analysis and flow cytometry.

Authors:  L L Lanier; E G Engleman; P Gatenby; G F Babcock; N L Warner; L A Herzenberg
Journal:  Immunol Rev       Date:  1983       Impact factor: 12.988

Review 4.  Human NK cells: light and electron microscopic characteristics.

Authors:  G F Babcock; J H Phillips
Journal:  Surv Immunol Res       Date:  1983

5.  Delineation of an effector population responsible for natural killing and antibody-dependent cellular cytotoxicity in man.

Authors:  J Breard; E L Reinherz; C O'Brien; S F Schlossman
Journal:  Clin Immunol Immunopathol       Date:  1981-01

6.  Evidence by reactivity with hybridoma antibodies for a probable myeloid origin of peripheral blood cells active in natural cytotoxicity and antibody-dependent cell-mediated cytotoxicity.

Authors:  H D Kay; D A Horwitz
Journal:  J Clin Invest       Date:  1980-10       Impact factor: 14.808

7.  Large granular lymphocytes in human peripheral blood: ultrastructural and cytochemical characterization of the granules.

Authors:  C E Grossi; A Cadoni; A Zicca; A Leprini; M Ferrarini
Journal:  Blood       Date:  1982-02       Impact factor: 22.113

8.  A monoclonal antibody reactive with the human cytotoxic/suppressor T cell subset previously defined by a heteroantiserum termed TH2.

Authors:  E L Reinherz; P C Kung; G Goldstein; S F Schlossman
Journal:  J Immunol       Date:  1980-03       Impact factor: 5.422

9.  The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique.

Authors:  R C Graham; M J Karnovsky
Journal:  J Histochem Cytochem       Date:  1966-04       Impact factor: 2.479

10.  Antigens on human monocytes identified by monoclonal antibodies.

Authors:  R F Todd; L M Nadler; S F Schlossman
Journal:  J Immunol       Date:  1981-04       Impact factor: 5.422
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  2 in total

1.  Leu-7-positive cells with monocyte phenotype show different ultrastructural features in comparison to Leu-7-positive cells with T-cell phenotype.

Authors:  G C Manara; G De Panfilis; C Ferrari; A Bonati; G Rocchi; R Scandroglio
Journal:  Histochemistry       Date:  1985

Review 2.  Biology of natural killer cells.

Authors:  G Trinchieri
Journal:  Adv Immunol       Date:  1989       Impact factor: 3.543
  2 in total

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