Literature DB >> 6386096

Inhibitory effect of syphilitic rabbit serum on DNA synthesis in rabbit cells in vitro.

G H Wong, B Steiner, R Strugnell, S Faine, S Graves.   

Abstract

A previously described toxic factor associated with Treponema pallidum (Nichols) and found in extracts of syphilitic rabbit testes has now also been detected in syphilitic rabbit serum. The toxic factor, which inhibits DNA synthesis in baby rabbit genital organ (BRGO) cells in vitro, is present in rabbit serum up to 30 days after infection with T pallidum.

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Year:  1984        PMID： 6386096      PMCID： PMC1046339          DOI： 10.1136/sti.60.5.285

Source DB:  PubMed          Journal:  Br J Vener Dis        ISSN： 0007-134X


  9 in total

Review 1.  Why is the infectious stage of syphilis prolonged?

Authors:  D J Wright; A S Grimble
Journal:  Br J Vener Dis       Date:  1974-02

2.  Electrophysiological dysfunction and cellular disruption of sensory neurones during incubation with Treponema pallidum.

Authors:  S G Oakes; L A Repesh; R S Pozos; T J Fitzgerald
Journal:  Br J Vener Dis       Date:  1982-08

Review 3.  Pathogenesis and immunology of Treponema pallidum.

Authors:  T J Fitzgerald
Journal:  Annu Rev Microbiol       Date:  1981       Impact factor: 15.500

4.  Morphological destruction of cultured cells by the attachment of Treponema pallidum.

Authors:  T J Fitzgerald; L A Repesh; S G Oakes
Journal:  Br J Vener Dis       Date:  1982-02

Review 5.  Cell-mediated immunity during syphilis.

Authors:  C S Pavis; J D Folds; J B Baseman
Journal:  Br J Vener Dis       Date:  1978-06

6.  Cytotoxicity of ascorbate and other reducing agents towards cultured fibroblasts as a result of hydrogen peroxide formation.

Authors:  B Peterkofsky; W Prather
Journal:  J Cell Physiol       Date:  1977-01       Impact factor: 6.384

7.  Suppression of lymphocyte response to concanavalin A by mucopolysaccharide material from Treponema pallidum-infected rabbits.

Authors:  R F Bey; R C Johnson; T J Fitzgerald
Journal:  Infect Immun       Date:  1979-10       Impact factor: 3.441

8.  Inhibition of macromolecular synthesis in cultured rabbit cells by Treponema pallidum (Nichols).

Authors:  G H Wong; B M Steiner; S Graves
Journal:  Infect Immun       Date:  1983-08       Impact factor: 3.441

9.  Cultivation of virulent Treponema pallidum in tissue culture.

Authors:  A H Fieldsteel; D L Cox; R A Moeckli
Journal:  Infect Immun       Date:  1981-05       Impact factor: 3.441
  9 in total

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