| Literature DB >> 6386038 |
R E Fray, O A Husain, A C To, K C Watts, S Lader, G T Rogers, J Taylor-Papadimitriou, N F Morris.
Abstract
This study was designed to determine whether immunohistochemical stains for tumour-associated markers may be useful in the detection and differential diagnosis of premalignant and malignant lesions of the cervix. The expression of four markers detected by monoclonal antibodies, human milk fat globule 1 and 2 (HMFG-1 and 2), Ca1 and anti-carcinoembryonic antigen (anti-CEA) on conventional histological sections of various cervical lesions has been investigated. None of these markers was specific for neoplastic lesions of the cervix and all four markers were expressed by metaplastic as well as neoplastic cells, and it was concluded that their application in the histopathological examination of the cervix is limited.Entities:
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Year: 1984 PMID： 6386038 DOI： 10.1111/j.1471-0528.1984.tb03684.x
Source DB: PubMed Journal: Br J Obstet Gynaecol ISSN： 0306-5456