| Literature DB >> 6386002 |
V L Beckett, D L Conn, V Fuster, P J Osmundson, C G Strong, E Y Chao, J H Chesebro, W M O'Fallon.
Abstract
In a randomized, double-blind, controlled study, 28 patients with early scleroderma received dipyridamole (225 mg/day) and aspirin (975 mg/day) or placebo for 1-2 years. No significant clinical or objective laboratory improvement was noted in either group. Platelet survival time, plasma renin activity, and coagulation tests were not predictive of disease course. Biomechanical and vascular tests of the hands correlated with clinical extent of skin induration and presence of finger ulcers, respectively.Entities:
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Year: 1984 PMID： 6386002 DOI： 10.1002/art.1780271009
Source DB: PubMed Journal: Arthritis Rheum ISSN： 0004-3591