Literature DB >> 638444

Cure of intractable watery diarrhoea by excision of a vipoma.

I M Modlin, S R Bloom, A Barnes, R B Welbourn.   

Abstract

A 56-year-old man suffered unexplained watery diarrhoea for 5 years which ultimately produced quadraparesis due to serve potassium depletion. All investigations were negative until demonstration of elevated plasma vasoactive intestinal peptide (VIP) indicated the presence of a vipoma. Removal of the VIP-producing tumour tissue--an adrenal ganglioneuroma--resulted in complete cure. Plasma VIP measurement is thus a valuable diagnostic screen in such cases and can be used to predict prognosis and to guide further therapy.

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Year:  1978        PMID： 638444     DOI： 10.1002/bjs.1800650406

Source DB:  PubMed          Journal:  Br J Surg        ISSN： 0007-1323            Impact factor:   6.939


  3 in total

1.  Neuroendocrine tumors of the gut.

Authors:  P Durning; R B Galland; D M Nagorney; R B Welbourn
Journal:  World J Surg       Date:  1985-04       Impact factor: 3.352

2.  Primary Pancreatic Secretinoma: Further Evidence Supporting Secretin as a Diarrheogenic Hormone.

Authors:  William Y Chey; Wendy L Frankel; Sashwati Roy; Soma Datta; Chandan K Sen; Mary Dillhoff; Peter Muscarella; Konrad H Soergel; Ronald K Tompkins; Ta-Min Chang; Edward L Bradley; Edwin Christopher Ellison
Journal:  Ann Surg       Date:  2017-08       Impact factor: 12.969

3.  Watery diarrhoea with a vasoactive intestinal peptide-producing ganglioneuroblastoma.

Authors:  Y Iida; O Nose; H Kai; A Okada; T Mori; P K Lee; K Kakudo; N Yanaihara
Journal:  Arch Dis Child       Date:  1980-12       Impact factor: 3.791
  3 in total

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