Serial brain sonography in two children with leukomalacia and cerebral palsy.

Two premature neonates were followed by brain sonograms from the time of birth to eight and nine months of age respectively, and by clinical assessment until two years and eighteen months of age respectively. In both children, the sonograms demonstrated evidence of bilateral periventricular leukomalacia (infarction) with very little associated intracranial hemorrhage. (CT scans were performed shortly after birth as well.) White matter infarction was seen as multiple tiny cysts adjacent to the lateral angles of the lateral ventricles. Both children have cerebral palsy (spastic quadriplegia).