Literature DB >> 6383205

Identification of aminoglycoside-acetylating enzymes by high-pressure liquid chromatographic determination of their reaction products.

A M Lovering, L O White, D S Reeves.   

Abstract

A method to identify the aminoglycoside-acetyltransferase (AAC) enzymes AAC(3), AAC(2') and AAC(6') by high-pressure liquid chromatographic characterization of their products of reaction with tobramycin or sisomicin is described. Conditions are given for the chromatography of kanamycin A, netilmicin, neomycin, and apramycin, and their products of reaction, if any, with the three AAC enzymes are listed.

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Year:  1984        PMID： 6383205      PMCID： PMC179905          DOI： 10.1128/AAC.26.1.10

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  9 in total

1.  R-factor mediated gentamicin resistance: A new enzyme which modifies aminoglycoside antibiotics.

Authors:  R Benveniste; J Davies
Journal:  FEBS Lett       Date:  1971-05-20       Impact factor: 4.124

Review 2.  Plasmid-determined resistance to antimicrobial agents.

Authors:  J Davies; D I Smith
Journal:  Annu Rev Microbiol       Date:  1978       Impact factor: 15.500

3.  Enzymatic modification of aminoglycoside antibiotics: 3-N-acetyltransferase with broad specificity that determines resistance to the novel aminoglycoside apramycin.

Authors:  J Davies; S O'Connor
Journal:  Antimicrob Agents Chemother       Date:  1978-07       Impact factor: 5.191

4.  The use of aminoglycoside 2'-N-acetyltransferase for the assay of gentamicin in serum, plasma and urine.

Authors:  K P Shannon; I Phillips
Journal:  J Antimicrob Chemother       Date:  1977-01       Impact factor: 5.790

5.  Purification and properties of gentamicin acetyltransferase I.

Authors:  J W Williams; D B Northrop
Journal:  Biochemistry       Date:  1976-01-13       Impact factor: 3.162

6.  Gentamicin transposons.

Authors:  W E Farrar
Journal:  J Antimicrob Chemother       Date:  1980-01       Impact factor: 5.790

7.  HPLC in clinical microbiology laboratories.

Authors:  L O White
Journal:  J Antimicrob Chemother       Date:  1981-07       Impact factor: 5.790

8.  Aminoglycoside resistance in bacteria medicated by gentamicin acetyltransferase II, an enzyme modifying the 2'-amino group of aminoglycoside antibiotics.

Authors:  M Chevereau; P J Daniels; J Davies; F LeGoffic
Journal:  Biochemistry       Date:  1974-01-29       Impact factor: 3.162

9.  Outbreaks of hospital infection in southwest England caused by gentamicin-resistant Serratia marcescens.

Authors:  D W Bullock; J L Bidwell; D S Reeves; L O White; A Turner; D C Speller; P J Wilkinson
Journal:  J Hosp Infect       Date:  1982-09       Impact factor: 3.926
  9 in total
  4 in total

1.  Characterization of the chromosomal aac(6')-Ic gene from Serratia marcescens.

Authors:  K J Shaw; P N Rather; F J Sabatelli; P Mann; H Munayyer; R Mierzwa; G L Petrikkos; R S Hare; G H Miller; P Bennett; P Downey
Journal:  Antimicrob Agents Chemother       Date:  1992-07       Impact factor: 5.191

2.  Isolation, characterization, and DNA sequence analysis of an AAC(6')-II gene from Pseudomonas aeruginosa.

Authors:  K J Shaw; C A Cramer; M Rizzo; R Mierzwa; K Gewain; G H Miller; R S Hare
Journal:  Antimicrob Agents Chemother       Date:  1989-12       Impact factor: 5.191

3.  Molecular epidemiology of two genes encoding 3-N-aminoglycoside acetyltransferases AAC(3)I and AAC(3)II among gram-negative bacteria from a Spanish hospital.

Authors:  M Alvarez; M C Mendoza
Journal:  Eur J Epidemiol       Date:  1993-11       Impact factor: 8.082

4.  Spread of novel aminoglycoside resistance gene aac(6')-Iad among Acinetobacter clinical isolates in Japan.

Authors:  Yohei Doi; Jun-Ichi Wachino; Kunikazu Yamane; Naohiro Shibata; Tetsuya Yagi; Keigo Shibayama; Haru Kato; Yoshichika Arakawa
Journal:  Antimicrob Agents Chemother       Date:  2004-06       Impact factor: 5.191
  4 in total

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