Literature DB >> 638172

Transformation of arachidonic acid into thromboxane B2 by the homogenates of activated macrophages.

S I Murota, M Kawamura, I Morita.   

Abstract

The homogenates of activated macrophages obtained from liquid paraffin-injected guinea pig peritoneum were incubated with [14C]arachidonic acid or with radioactive prostaglandin endoperoside [14C]prostaglandin H2. The major radioactive metabolite in both cases was thromboxane B2, which was identified by NaBH4 reduction, rechromatography and autoradiography.

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Year:  1978        PMID： 638172

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  13 in total

1.  Localization of thromboxane synthase in human tissues by monoclonal antibody Tü 300.

Authors:  R Nüsing; G Sauter; P Fehr; U Dürmüller; M Kasper; F Gudat; V Ullrich
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1992

Review 2.  Eighth Gaddum Memorial Lecture. University of London Institute of Education, December 1980. Biological importance of prostacyclin.

Authors:  S Moncada
Journal:  Br J Pharmacol       Date:  1982-05       Impact factor: 8.739

Review 3.  The prostanoids in hemostasis and thrombosis: a review.

Authors:  J B Smith
Journal:  Am J Pathol       Date:  1980-06       Impact factor: 4.307

4.  Thromboxane synthase immunohistochemistry in inflammatory bowel disease.

Authors:  E Carty; C Nickols; R M Feakins; D S Rampton
Journal:  J Clin Pathol       Date:  2002-05       Impact factor: 3.411

5.  Thromboxane receptor signaling is required for fibronectin-induced matrix metalloproteinase 9 production by human and murine macrophages and is attenuated by the Arhgef1 molecule.

Authors:  John M Hartney; Claire E Gustafson; Russell P Bowler; Roberta Pelanda; Raul M Torres
Journal:  J Biol Chem       Date:  2011-11-15       Impact factor: 5.157

6.  Inhibitors of the 5-lipoxygenase pathway activate pannexin1 channels in macrophages via the thromboxane receptor.

Authors:  Hercules A da Silva-Souza; Maria Nathália de Lira; Naman K Patel; David C Spray; Pedro Muanis Persechini; Eliana Scemes
Journal:  Am J Physiol Cell Physiol       Date:  2014-07-30       Impact factor: 4.249

7.  Macrophage function in the Schistosoma mansoni egg-induced pulmonary granuloma. Role of arachidonic acid metabolites in macrophage Ia antigen expression.

Authors:  S L Kunkel; S W Chensue; M Plewa; G I Higashi
Journal:  Am J Pathol       Date:  1984-02       Impact factor: 4.307

8.  Effect of sodium n-butyrate on induction of prostaglandin synthase activity in cloned mastocytoma P-815 2-E-6 cells.

Authors:  Y Koshihara; M Kawamura; T Senshu; S Murota
Journal:  Biochem J       Date:  1981-01-15       Impact factor: 3.857

9.  Ipriflavone inhibits murine osteoclast formation in vitro.

Authors:  I Morita; K Sakaguchi; T Kurachi; S Murota
Journal:  Calcif Tissue Int       Date:  1992       Impact factor: 4.333

10.  The localization of thromboxane synthase in normal and pathological human kidney tissue using a monoclonal antibody Tü 300.

Authors:  R Nüsing; P M Fehr; F Gudat; E Kemeny; M J Mihatsch; V Ullrich
Journal:  Virchows Arch       Date:  1994       Impact factor: 4.064
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