Literature DB >> 6381086

Drug metabolism in spontaneously diabetic guinea pigs.

D E Cook, J D Jackson, M R Past, C M Lang, L P Bullock.   

Abstract

Both sexes of spontaneously diabetic guinea pigs exhibit hyperinsulinemia (greater than 4-fold normal). This diabetic state is associated with the inhibition of hepatic drug metabolism in males but not females.

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6381086     DOI： 10.1007/bf01951983

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  15 in total

1.  Resistance of rabbits and guinea pigs to the diabetogenic effect of streptozotocin.

Authors:  B Kushner; M Lazar; M Furman; T W Lieberman; I H Leopold
Journal:  Diabetes       Date:  1969-08       Impact factor: 9.461

2.  Hepatic enzyme activities in streptozotocin-diabetic rats before and after insulin treatment.

Authors:  A Y Chang; D I Schneider
Journal:  Diabetes       Date:  1971-02       Impact factor: 9.461

3.  Absence of cytosol effects on the rates of microsomal drug metabolism in alloxan and streptozotocin diabetic rats.

Authors:  M R Past; D E Cook
Journal:  Biochem Pharmacol       Date:  1980-09-15       Impact factor: 5.858

Review 4.  Sex-related differences in drug metabolism.

Authors:  R Kato
Journal:  Drug Metab Rev       Date:  1974       Impact factor: 4.518

5.  Liver microsomal cytochrome P-450 and related monooxygenase activities in genetically hyperglycemic (ob/ob and db/db) and lean streptozotocin-treated mice.

Authors:  E Rouer; J P Leroux
Journal:  Biochem Pharmacol       Date:  1980-07-01       Impact factor: 5.858

6.  Diabetes mellitus in the guinea pig.

Authors:  C M Lang; B L Munger
Journal:  Diabetes       Date:  1976-05       Impact factor: 9.461

7.  The spontaneously diabetic Wistar rat. Metabolic and morphologic studies.

Authors:  A F Nakhooda; A A Like; C I Chappel; F T Murray; E B Marliss
Journal:  Diabetes       Date:  1977-02       Impact factor: 9.461

8.  Effect of diabetes on rat liver cytochrome P-450. Evidence for a unique diabetes-dependent rat liver cytochrome P-450.

Authors:  M R Past; D E Cook
Journal:  Biochem Pharmacol       Date:  1982-10-15       Impact factor: 5.858

9.  The effects of starvation and experimental diabetes on phosphoenol-pyruvate carboxykinase in the guinea pig.

Authors:  K R Elliott; C I Pogson
Journal:  Biochem J       Date:  1977-05-15       Impact factor: 3.857

10.  Differential effects of diabetes on microsomal metabolism of various substrates. Comparison of streptozotocin and spontaneously diabetic Wistar rats.

Authors:  B L Warren; R Pak; M Finlayson; L Gontovnick; G Sunahara; G D Bellward
Journal:  Biochem Pharmacol       Date:  1983-01-15       Impact factor: 5.858
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.