Literature DB >> 6380557

Effect of bacterial endotoxin on body temperature, plasma zinc and plasma concentrations of the acute-phase protein serum amyloid p component in mice.

S Poole, A H Gordon, M Baltz, B E Stenning.   

Abstract

Bacterial endotoxin and lipid A evoked dose-dependent increases in body temperature and plasma SAP concentrations and dose-dependent falls in plasma zinc concentrations in mice. The respective sensitivities of the three variables to lipid A or to whole endotoxin had the relation SAP greater than Zinc much greater than body temperature; zinc and SAP responses were evoked by less than 1 ng lipid A/endotoxin. Pretreatment with indomethacin prevented only the temperature response to lipid A. Pretreatment with dexamethasone did not affect the temperature response but diminished the zinc response and enhanced the SAP response to lipid A.

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Year:  1984        PMID： 6380557      PMCID： PMC2040987     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  16 in total

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7.  Identification of glucocorticoid-induced genes in rat hepatoma cells by isolation of cloned cDNA sequences.

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Journal:  J Exp Med       Date:  1976-10-01       Impact factor: 14.307
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  6 in total

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Authors:  K Goelst; D Mitchell; H Laburn
Journal:  J Physiol       Date:  1991-09       Impact factor: 5.182

2.  Pharmacological validation of a novel animal model of anticipatory anxiety in mice.

Authors:  A Lecci; F Borsini; G Volterra; A Meli
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Journal:  Proc Natl Acad Sci U S A       Date:  2005-05-26       Impact factor: 11.205

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Journal:  J Clin Immunol       Date:  1992-11       Impact factor: 8.317

6.  Isolation and characterization of pharmaceutical grade human pentraxins, serum amyloid P component and C-reactive protein, for clinical use.

Authors:  Mark B Pepys; J Ruth Gallimore; Joanne Lloyd; Zhanhong Li; David Graham; Graham W Taylor; Stephan Ellmerich; Palma P Mangione; Glenys A Tennent; Winston L Hutchinson; David J Millar; Gary Bennett; John More; David Evans; Yogesh Mistry; Stephen Poole; Philip N Hawkins
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  6 in total

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