Alcohol and ischemic heart disease: a review.

Evidence from epidemiological studies suggests that consumption of alcohol at moderate levels might be protective against IHD. The alcohol-IHD relationship appears to be U-shaped, so that the risk of IHD associated with moderate levels of alcohol consumption is lower than that for abstainers and heavy drinkers. However, the effects of alcohol upon the risk of IHD must be examined in the context of its overall effects upon health. When this is done, the potential benefits are not clear-cut. This paper reviews the epidemiological evidence relating to the alcohol-IHD association, considers the mechanisms by which alcohol might exert its effects upon IHD risk, and suggests some avenues for future research in this area.