Literature DB >> 6379679

A multi-centre study of sulindac versus naproxen in the treatment of elderly osteoarthritic patients.

P G Janke, J B Diggins, W J Currie, P K Dasgupta, E N Glick, N A Sheikh.   

Abstract

Ninety-five geriatric patients with osteoarthritis of the hip and/or knee were entered into an open parallel group study of sulindac (400 mg/day) and naproxen (500 mg/day), both given in twice-daily regimens. Patients received the drugs for 12 weeks. Both drugs produced improvements in the patients' overall condition. There were no statistically significant differences between the effects of the two drugs. Overall, both drugs proved beneficial and well tolerated.

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Year:  1984        PMID: 6379679

Source DB:  PubMed          Journal:  Pharmatherapeutica        ISSN: 0308-051X


  2 in total

1.  Pharmacokinetics of naproxen in elderly patients.

Authors:  R M McVerry; J Lethbridge; N Martin; S K Mukerjee; T Littler; R Tallis; R Sibeon; M L Orme
Journal:  Eur J Clin Pharmacol       Date:  1986       Impact factor: 2.953

Review 2.  Naproxen. A reappraisal of its pharmacology, and therapeutic use in rheumatic diseases and pain states.

Authors:  P A Todd; S P Clissold
Journal:  Drugs       Date:  1990-07       Impact factor: 9.546

  2 in total

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