Literature DB >> 637925

Radionuclide imaging of metastases from renal-cell carcinoma by 131I-labeled antitumor antibody.

P Belitsky, T Ghose, J Aquino, J Tai, A S MacDonald.   

Abstract

On immunofluorescence assay, goat antisera reacted with renal-cell carcinomas from 20 patients, but not with adult normal human tissues (including patient's normal kidney). After in travenous injection, the 131I-labeled antibody localized preferentially in metastatic renal carcinoma in 6 consecutive patients. Labeled antitumor antibodies may have the specificity for tumor imagining which current radiopharmaceuticals lack.

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Year:  1978        PMID： 637925     DOI： 10.1148/126.2.515

Source DB:  PubMed          Journal:  Radiology        ISSN： 0033-8419            Impact factor:   11.105


  4 in total

1.  Production of a bifunctional hybrid molecule B72.3/metallothionein-1 by protein engineering.

Authors:  J Xiang; J Koropatnick; Y Qi; X Luo; T Moyana; K Li; Y Chen
Journal:  Immunology       Date:  1993-04       Impact factor: 7.397

2.  Radioimmunolocalization of human brain tumours: biodistribution of radiolabelled monoclonal antibody UJ13A.

Authors:  R B Richardson; A G Davies; S P Bourne; G E Staddon; D H Jones; J T Kemshead; H B Coakham
Journal:  Eur J Nucl Med       Date:  1986

Review 3.  Antibody-mediated targeting in the treatment and diagnosis of cancer: an overview.

Authors:  C H Ford; A G Casson
Journal:  Cancer Chemother Pharmacol       Date:  1986       Impact factor: 3.333

4.  Localization of 131I-labeled p97-specific Fab fragments in human melanoma as a basis for radiotherapy.

Authors:  S M Larson; J A Carrasquillo; K A Krohn; J P Brown; R W McGuffin; J M Ferens; M M Graham; L D Hill; P L Beaumier; K E Hellström
Journal:  J Clin Invest       Date:  1983-12       Impact factor: 14.808
  4 in total

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