Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The influence of indomethacin and sulindac on some pharmacological actions of atenolol in hypertensive patients.

Literature DB >> 6378233

The influence of indomethacin and sulindac on some pharmacological actions of atenolol in hypertensive patients.

A Salvetti, R Pedrinelli, P Alberici, A Magagna, B Abdel-Haq.

Abstract

Indomethacin and sulindac were used as tools to study the role of renal and/or systemic prostaglandins in the pharmacological response to atenolol. Patients receiving chronic treatment with atenolol 100 mg received indomethacin 50 mg twice daily or sulindac 200 mg twice daily in a randomised crossover trial. Indomethacin significantly reduced the antihypertensive action of atenolol while sulindac had no effect. The role that systemic and/or renal prostaglandins may play in the antihypertensive action of atenolol is discussed with reference to renal PGI2 production and inhibition of platelet cyclo-oxygenase.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1984 PMID： 6378233 PMCID： PMC1463273 DOI： 10.1111/j.1365-2125.1984.tb02442.x

Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335

6 in total

1. Modification by indomethacin of the blood pressure lowering effect of pindolol and propranolol in conscious rabbits.

Authors: V Durão; J M Rico
Journal: Eur J Pharmacol Date: 1977-06-15 Impact factor: 4.432

2. Control of the enzyme systems in plasma renin activity measurement by angiotensin I radioimmunoassay.

Authors: G C Zucchelli; R Malvano; U Rosa; A Salvetti
Journal: J Nucl Biol Med Date: 1973 Oct-Dec

3. Radioimmunoassay of serum thromboxane B2: a simple method of assessing pharmacologic effects on platelet function.

Authors: C Patrono; G Ciabattoni; F Pugliese; E Pinca; G Castrucci; A De Salvo; M A Satta; M Parachini
Journal: Adv Prostaglandin Thromboxane Res Date: 1980

4. Effects of indomethacin alone and during diuretic or beta-adrenoreceptor-blockade therapy on blood pressure and the renin system in essential hypertension.

Authors: J A Lopez-Ovejero; M A Weber; J I Drayer; J E Sealey; J H Laragh
Journal: Clin Sci Mol Med Suppl Date: 1978-12

5. Interaction between oxprenolol and indomethacin on blood pressure in essential hypertensive patients.

Authors: A Salvetti; F Arzilli; R Pedrinelli; P Beggi; M Motolese
Journal: Eur J Clin Pharmacol Date: 1982 Impact factor: 2.953

6. Evidence for a direct stimulatory effect of prostacyclin on renin release in man.

Authors: C Patrono; F Pugliese; G Ciabattoni; P Patrignani; A Maseri; S Chierchia; B A Peskar; G A Cinotti; B M Simonetti; A Pierucci
Journal: J Clin Invest Date: 1982-01 Impact factor: 14.808

6 in total

13 in total

10. Cutaneous blood flow changes and weal induced by intradermal bradykinin following pretreatment with indomethacin and captopril.

Authors: T C Wa; E D Cooke; P Turner
Journal: Eur J Clin Pharmacol Date: 1993 Impact factor: 2.953

The influence of indomethacin and sulindac on some pharmacological actions of atenolol in hypertensive patients.

1. Modification by indomethacin of the blood pressure lowering effect of pindolol and propranolol in conscious rabbits.

2. Control of the enzyme systems in plasma renin activity measurement by angiotensin I radioimmunoassay.

3. Radioimmunoassay of serum thromboxane B2: a simple method of assessing pharmacologic effects on platelet function.

4. Effects of indomethacin alone and during diuretic or beta-adrenoreceptor-blockade therapy on blood pressure and the renin system in essential hypertension.

5. Interaction between oxprenolol and indomethacin on blood pressure in essential hypertensive patients.

6. Evidence for a direct stimulatory effect of prostacyclin on renin release in man.

Review 1. beta-blockers. Drug interactions of clinical significance.

Review 2. Newer ACE inhibitors. A look at the future.

Review 3. Atenolol. A reappraisal of its pharmacological properties and therapeutic use in cardiovascular disorders.

Review 4. Pharmacokinetic drug interactions with nonsteroidal anti-inflammatory drugs.

Review 5. NSAIDs and blood pressure. Clinical importance for older patients.

Review 6. Clinical pharmacokinetics of sulindac. A dynamic old drug.

7. Interaction of indomethacin and sulindac with labetalol.

Review 8. Interactions of NSAIDs with diuretics and beta-blockers mechanisms and clinical implications.

Review 9. Do nonsteroidal anti-inflammatory drugs interfere with blood pressure control in hypertensive patients?

10. Cutaneous blood flow changes and weal induced by intradermal bradykinin following pretreatment with indomethacin and captopril.