| Literature DB >> 6377990 |
K Jeraj, J Basgen, R M Hardy, C A Osborne, A F Michael.
Abstract
Renal tissue from 12 dogs with spontaneous diabetes and 16 control dogs were studied by light, immunofluorescence, and electron microscopies. Significant linear staining for immunoglobulin G and albumin were observed in the glomerular and tubular basement membranes of dogs with spontaneous diabetes--similar to that observed in human diabetes. On immunohistochemical grounds, it would appear that the dog with spontaneous diabetes is an appropriate model of diabetes in persons.Entities:
Mesh:
Year: 1984 PMID: 6377990
Source DB: PubMed Journal: Am J Vet Res ISSN: 0002-9645 Impact factor: 1.156