Sjögren's syndrome with pseudolymphoma 13 years after Hodgkin's disease.

A patient who had Hodgkin's disease at age 11 that was cured by radiation therapy, had nonspecific adenopathy at age 20. When he was 24 years old, the symptoms of Sjögren's syndrome developed, and this diagnosis was confirmed by biopsy of the lip. The patient subsequently had dyspnea and a diffuse pulmonary infiltrate which, at open lung biopsy, was diagnosed as pseudolymphoma and has responded to cytotoxic chemotherapy. This is the first reported case of Sjögren's syndrome and pseudolymphoma following the cure of a malignant lymphoma. The interrelationship between lymphoid malignancies, autoimmune diseases, and pseudolymphoma is herein discussed.