Literature DB >> 6376301

[Stimulation of wound healing by tetrachlordecaoxide. Results of a randomized double-blind study].

J Hinz, H Hautzinger, J Helling, G Schirren, G Sell, K W Stahl, F W Kühne.   

Abstract

In 38 patients with chronic therapeutically resistant wounds, which, in 25 cases, had been existing for more than one year, Tetrachlorodecaoxide ( TCDO ) in a water solution containing glycerin was analyzed for its capacity to induce wound healing and compared in this respect to the standard in moist wound treatment, physiological sodium chloride. The results of the clinical trial demonstrate that the TCDO solution is significantly superior to physiological saline in local wound treatment regarding the degree of wound smear reduction, the formation of wound granulation tissue, the stimulation of epithelisation on the wound borders and the shrinking of the wound surface. The differences in therapeutic efficiency are so large that, in spite of the relatively small patient samples (21 + 17) it was possible to verify the superiority of a method for wound treatment in a randomized double blind clinical trial.

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Year:  1984        PMID: 6376301

Source DB:  PubMed          Journal:  Fortschr Med        ISSN: 0015-8178


  2 in total

1.  New aspects on the pathophysiology of wound infection and wound healing--the problem of lowered oxygen pressure in the tissue.

Authors:  H H Kühne; U Ullmann; F W Kühne
Journal:  Infection       Date:  1985 Mar-Apr       Impact factor: 3.553

2.  Anti-inflammatory properties of a novel wound healing and immunomodulating agent, tetrachlorodecaoxygen complex (TCDO).

Authors:  M Tissot; M Roch-Arveiller; J Mathieu; J P Giroud; K W Stahl
Journal:  Agents Actions       Date:  1990-11
  2 in total

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