Literature DB >> 6376191

Antibody-mediated immune response in the bat, Pteropus giganteus.

A K Chakraborty, A K Chakravarty.   

Abstract

Among mammals, the Chiroptera (Bats) have been perhaps the least studied with respect to systematic accounts of immune responses. To resolve this omission in comparative immunology, we have begun to analyze aspects of immunity of the large frugivorous bat, Pteropus giganteus with respect to antibody secreting plaque forming cells and serum antibodies as measured by haemagglutination titres. Homologous complement was more effective than guinea pig or rabbit complement in lysing SRBC for developing plaques. Kinetic of antibody response to three different doses of SRBC has been studied. We observed a peak primary response and its decay after a single antigenic challenge which were notably delayed, and a same dose of antigen could produce 2-Mercaptoethanol resistant PFC and HA-tires.

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Year:  1984        PMID: 6376191     DOI: 10.1016/0145-305x(84)90048-x

Source DB:  PubMed          Journal:  Dev Comp Immunol        ISSN: 0145-305X            Impact factor:   3.636


  13 in total

1.  Phylogeography, population dynamics, and molecular evolution of European bat lyssaviruses.

Authors:  Patricia L Davis; Edward C Holmes; Florence Larrous; Wim H M Van der Poel; Kirsten Tjørnehøj; Wladimir J Alonso; Hervé Bourhy
Journal:  J Virol       Date:  2005-08       Impact factor: 5.103

2.  Transcriptome Profiling of the Virus-Induced Innate Immune Response in Pteropus vampyrus and Its Attenuation by Nipah Virus Interferon Antagonist Functions.

Authors:  Nicole B Glennon; Omar Jabado; Michael K Lo; Megan L Shaw
Journal:  J Virol       Date:  2015-05-13       Impact factor: 5.103

Review 3.  Changing resource landscapes and spillover of henipaviruses.

Authors:  Maureen K Kessler; Daniel J Becker; Alison J Peel; Nathan V Justice; Tamika Lunn; Daniel E Crowley; Devin N Jones; Peggy Eby; Cecilia A Sánchez; Raina K Plowright
Journal:  Ann N Y Acad Sci       Date:  2018-08-23       Impact factor: 5.691

4.  Pteropid bats are confirmed as the reservoir hosts of henipaviruses: a comprehensive experimental study of virus transmission.

Authors:  Kim Halpin; Alex D Hyatt; Rhys Fogarty; Deborah Middleton; John Bingham; Jonathan H Epstein; Sohayati Abdul Rahman; Tom Hughes; Craig Smith; Hume E Field; Peter Daszak
Journal:  Am J Trop Med Hyg       Date:  2011-11       Impact factor: 2.345

5.  Immunoglobulin heavy chain diversity in Pteropid bats: evidence for a diverse and highly specific antigen binding repertoire.

Authors:  Michelle L Baker; Mary Tachedjian; Lin-Fa Wang
Journal:  Immunogenetics       Date:  2010-02-17       Impact factor: 2.846

Review 6.  From bats to pangolins: new insights into species differences in the structure and function of the immune system.

Authors:  Patrick J Haley
Journal:  Innate Immun       Date:  2022-05-04       Impact factor: 2.951

7.  Immunological Control of Viral Infections in Bats and the Emergence of Viruses Highly Pathogenic to Humans.

Authors:  Tony Schountz; Michelle L Baker; John Butler; Vincent Munster
Journal:  Front Immunol       Date:  2017-09-11       Impact factor: 7.561

8.  Experimental Zika virus infection of Jamaican fruit bats (Artibeus jamaicensis) and possible entry of virus into brain via activated microglial cells.

Authors:  Ashley Malmlov; Collin Bantle; Tawfik Aboellail; Kaitlyn Wagner; Corey L Campbell; Miles Eckley; Nunya Chotiwan; Rebekah C Gullberg; Rushika Perera; Ronald Tjalkens; Tony Schountz
Journal:  PLoS Negl Trop Dis       Date:  2019-02-04

9.  Purification and characterisation of immunoglobulins from the Australian black flying fox (Pteropus alecto) using anti-fab affinity chromatography reveals the low abundance of IgA.

Authors:  James W Wynne; Antonio Di Rubbo; Brian J Shiell; Gary Beddome; Christopher Cowled; Grantley R Peck; Jing Huang; Samantha L Grimley; Michelle L Baker; Wojtek P Michalski
Journal:  PLoS One       Date:  2013-01-07       Impact factor: 3.240

10.  Detection of specific antibody responses to vaccination in variable flying foxes (Pteropus hypomelanus).

Authors:  James F X Wellehan; Linda G Green; Diane G Duke; Shadi Bootorabi; Darryl J Heard; Paul A Klein; Elliott R Jacobson
Journal:  Comp Immunol Microbiol Infect Dis       Date:  2008-02-01       Impact factor: 2.268

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