Literature DB >> 6374173

Enhanced immune response in the urinary tract of the rat following vaginal immunization.

J Jensen, D T Uehling, K Kim, K Seagren-Rasmussen, E Balish.   

Abstract

The immune response in the rat urinary tract was assessed by an enzyme-linked immunosorbent assay for immunoglobulins following vaginal immunization and subsequent intravesical challenge with live E. coli 06. Vaginally immunized rats showed a strong and rapid bladder immune response following intravesical challenge, in contrast to nonimmunized control rats. The immune response was localized to the urinary tract in that antibody to E. coli 06 was not detected in serum, saliva and vaginal washes from immunized rats.

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Year:  1984        PMID： 6374173     DOI： 10.1016/s0022-5347(17)49511-5

Source DB:  PubMed          Journal:  J Urol        ISSN： 0022-5347            Impact factor:   7.450


  3 in total

1.  Induction of protective immunity after escherichia coli bladder infection in primates. Dependence of the globoside-specific P-fimbrial tip adhesin and its cognate receptor.

Authors:  M Söderhäll; S Normark; K Ishikawa; K Karlsson; S Teneberg; J Winberg; R Möllby
Journal:  J Clin Invest       Date:  1997-07-15       Impact factor: 14.808

2.  Secretory immunoglobulin A and inhibitory activity of bacterial adherence to epithelial cells in urine from patients with urinary tract infections.

Authors:  A Trinchieri; L Braceschi; D Tiranti; S Dell'Acqua; A Mandressi; E Pisani
Journal:  Urol Res       Date:  1990

3.  Local and systemic antibody responses accompany spontaneous resolution of experimental cystitis in cynomolgus monkeys.

Authors:  W J Hopkins; D T Uehling; E Balish
Journal:  Infect Immun       Date:  1987-09       Impact factor: 3.441
  3 in total

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