Literature DB >> 6373374

The effect of insulin on Fru-2,6-P2 levels in human fibroblasts.

M Farnararo, V Vasta, P Bruni, A D'Alessandro.   

Abstract

We report that fructose 2,6-bisphosphate (Fru-2,6-P2) levels in quiescent human fibroblasts stimulated with insulin treatment increase in a time- and dose-dependent manner. The biochemical role of the sugar phosphate in the cellular response to the hormone which controls carbohydrate metabolism and acts as mitogenic factor is discussed.

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Year:  1984        PMID： 6373374     DOI： 10.1016/0014-5793(84)80470-6

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  8 in total

Review 1.  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis.

Authors:  Mark H Rider; Luc Bertrand; Didier Vertommen; Paul A Michels; Guy G Rousseau; Louis Hue
Journal:  Biochem J       Date:  2004-08-01       Impact factor: 3.857

2.  Continuous monitoring of receptor-mediated changes in the metabolic rates of living cells.

Authors:  J C Owicki; J W Parce; K M Kercso; G B Sigal; V C Muir; J C Venter; C M Fraser; H M McConnell
Journal:  Proc Natl Acad Sci U S A       Date:  1990-05       Impact factor: 11.205

Review 3.  Role of fructose 2,6-bisphosphate in the control of glycolysis in mammalian tissues.

Authors:  L Hue; M H Rider
Journal:  Biochem J       Date:  1987-07-15       Impact factor: 3.857

4.  Phosphofructokinase 2 and glycolysis in HT29 human colon adenocarcinoma cell line. Regulation by insulin and phorbol esters.

Authors:  C Denis-Pouxviel; T Gauthier; D Daviaud; J C Murat
Journal:  Biochem J       Date:  1990-06-01       Impact factor: 3.857

5.  Control of glycolysis in cultured chick embryo hepatocytes. Fructose 2,6-bisphosphate content and phosphofructokinase-1 activity are stimulated by insulin and epidermal growth factor.

Authors:  M J Hamer; A J Dickson
Journal:  Biochem J       Date:  1990-08-01       Impact factor: 3.857

6.  Phorbol 12-myristate 13-acetate and insulin increase the concentration of fructose 2,6-bisphosphate and stimulate glycolysis in chicken embryo fibroblasts.

Authors:  L Bosca; G G Rousseau; L Hue
Journal:  Proc Natl Acad Sci U S A       Date:  1985-10       Impact factor: 11.205

7.  Effect of glutamine on fructose 2,6-bisphosphate and on glucose metabolism in HeLa cells and in chick-embryo fibroblasts.

Authors:  M Mojena; L Bosca; L Hue
Journal:  Biochem J       Date:  1985-12-01       Impact factor: 3.857

8.  Fructose 2,6-bisphosphate metabolism during megakaryocytic differentiation of K562 and MEG-01 cells.

Authors:  E Meacci; V Vasta; M Farnararo; P Bruni
Journal:  Mol Cell Biochem       Date:  1996-03-23       Impact factor: 3.396
  8 in total

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