Auditory deficits in multiple sclerosis: a review.

This article reviews available clinical and psychophysical data concerning the effects of multiple sclerosis (MS) on basic auditory processes. On the basis of the data, it is suggested that the presence of auditory deficits should be sought in MS patients. This is especially important in light of recent psychophysical evidence suggesting that subtle auditory problems present in affected individuals may not always be detectable via conventional clinical testing. These data also provide an alternate means of interpreting various aspects of impaired auditory functioning in MS patients, and aid in generating new hypotheses regarding the possible consequences of demyelination on normal auditory perception. Finally, new ways of testing such hypotheses are proposed, and possible directions for future research are suggested.