CT scanning and schizophrenia: a review.

Methods currently used to quantify CT scans are reviewed, and the benefits and limitations of linear and area measurements are compared. The evidence suggesting that a subgroup of schizophrenics has significantly larger ventricles than normal is examined, with the conclusion that, while not diagnostically useful, ventricular enlargement is of use for theories of pathogenesis. Sulcal enlargement, brain density changes and cerebral asymmetry are also considered.