Literature DB >> 6370294

Dermatological aspects of the use of Cyclosporin A for prophylaxis of graft-versus-host disease.

J I Harper, J R Kendra, S Desai, R C Staughton, A J Barrett, J R Hobbs.   

Abstract

Oral Cyclosporin A (CyA) was given for the prophylaxis of graft-versus-host disease (GVHD) to sixty-seven patients receiving a bone marrow transplant, and was found to be extremely effective in reducing the severity of acute GVHD. Side-effects of CyA included hypertrichosis, gum hypertrophy, and a rare but serious 'capillary leak' syndrome.

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Year:  1984        PMID: 6370294     DOI: 10.1111/j.1365-2133.1984.tb04662.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  6 in total

1.  Reconstitution of the In Vitro Activity of the Cyclosporine-Specific P450 Hydroxylase from Sebekia benihana and Development of a Heterologous Whole-Cell Biotransformation System.

Authors:  Li Ma; Lei Du; Hui Chen; Yue Sun; Shan Huang; Xianliang Zheng; Eung-Soo Kim; Shengying Li
Journal:  Appl Environ Microbiol       Date:  2015-07-06       Impact factor: 4.792

2.  Cyclosporin-A-induced hair growth in human renal allograft recipients and alopecia areata.

Authors:  W Gebhart; J B Schmidt; M Schemper; J Spona; H Kopsa; J Zazgornik
Journal:  Arch Dermatol Res       Date:  1986       Impact factor: 3.017

Review 3.  Cutaneous graft versus host disease.

Authors:  J I Harper
Journal:  Br Med J (Clin Res Ed)       Date:  1987-08-15

Review 4.  Graft versus host diseases: new versions of old problems?

Authors:  A M Denman
Journal:  Br Med J (Clin Res Ed)       Date:  1985-03-02

5.  Cyclosporin A induced augmentation of the beta-adrenergic adenylate cyclase response of pig epidermis.

Authors:  N Kato; K M Halprin; J R Taylor; A Ohkawara
Journal:  Arch Dermatol Res       Date:  1988       Impact factor: 3.017

Review 6.  The psoriatic epidermal lesion and anagen hair growth may share the same "switch-on" mechanism.

Authors:  R Paus; R E Link
Journal:  Yale J Biol Med       Date:  1988 Sep-Oct
  6 in total

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