Literature DB >> 6369208

[Bioavailability of cyclophosphamide following oral administration in high doses].

M Matthias, R Sohr, R Preiss, B Brockmann.   

Abstract

Mean rate of absorption of cyclophosphamide after oral administration from studies in which the drug is given in doses of 0,7 g/m2 body surface both orally and intravenously to the same 18 tumor patients is 87.7% (s - 21.1%). The drug may be administered orally with good bioavailability at the high dose.

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Year:  1984        PMID: 6369208     DOI: 10.1159/000215401

Source DB:  PubMed          Journal:  Onkologie        ISSN: 0378-584X


  3 in total

Review 1.  Clinical pharmacokinetics of cyclophosphamide.

Authors:  M J Moore
Journal:  Clin Pharmacokinet       Date:  1991-03       Impact factor: 6.447

2.  Pharmacokinetics of intravenous and oral cyclophosphamide in the presence of methotrexate and fluorouracil.

Authors:  E A De Bruijn; P H Slee; A T Van Oosterom; D W Lameijer; K J Roozendaal; U R Tjaden
Journal:  Pharm Weekbl Sci       Date:  1988-10-14

3.  Human CD4+CD25+ regulatory T cells are sensitive to low dose cyclophosphamide: implications for the immune response.

Authors:  Daniel Heylmann; Martina Bauer; Huong Becker; Stefaan van Gool; Nicole Bacher; Kerstin Steinbrink; Bernd Kaina
Journal:  PLoS One       Date:  2013-12-23       Impact factor: 3.240

  3 in total

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