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Literature DB >> 6368399

Defective phagocyte Aspergillus killing associated with recurrent pulmonary Aspergillus infections.

A Fietta, F Sacchi, P Mangiarotti, G Manara, G Gialdroni Grassi.

Abstract

An apparently healthy boy was suffering from recurrent Aspergillus infections. No classical conditions of immunodeficiency were found. Studies on the patient's phagocytic system revealed neutrophils and monocytes to function normally except in Aspergillus killing (microbicidal activity for bacteria and Candida was normal). Aspergillus killing mechanisms may be complex and peculiarly selective, possibly involving both oxygen-dependent and independent mechanisms.

Entities: Chemical Disease Species

Mesh：

Year: 1984 PMID： 6368399 DOI： 10.1007/bf01641016

Source DB: PubMed Journal: Infection ISSN： 0300-8126 Impact factor: 3.553

14 in total

Review 1. Infections in cancer patients.

Authors: G P Bodey
Journal: Cancer Treat Rev Date: 1975-06 Impact factor: 12.111

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Authors: J L Malo; R Hawkins; J Pepys
Journal: Thorax Date: 1977-06 Impact factor: 9.139

Review 3. Chronic granulomatous disease.

Authors: R B Johnston; S L Newman
Journal: Pediatr Clin North Am Date: 1977-05 Impact factor: 3.278

4. Disorders of candidacidal activity and other neutrophil functions in three cases of chronic candidiasis.

Authors: F Sacchi; M A Cisternino; A Clivio; F A Ferrari; A Fortunato; L Nespoli; A Beretta; A G Siccardi
Journal: Helv Paediatr Acta Date: 1979

5. Intracellular bactericidal activity of leukocytes in whole blood for the diagnosis of chronic granulomatous disease of childhood.

Authors: G T Keusch; S D Douglas; K Ugurbil
Journal: J Infect Dis Date: 1975-05 Impact factor: 5.226

Review 6. Hematologic malignancies and other marrow failure states: progress in the management of complicating infections.

Authors: A S Levine; S C Schimpff; R G Graw; R C Young
Journal: Semin Hematol Date: 1974-04 Impact factor: 3.851

7. Leukocyte myeloperoxidase deficiency and disseminated candidiasis: the role of myeloperoxidase in resistance to Candida infection.

Authors: R I Lehrer; M J Cline
Journal: J Clin Invest Date: 1969-08 Impact factor: 14.808

Review 4. Aspergillosis.

Authors: G P Bodey; S Vartivarian
Journal: Eur J Clin Microbiol Infect Dis Date: 1989-05 Impact factor: 3.267

4 in total

Defective phagocyte Aspergillus killing associated with recurrent pulmonary Aspergillus infections.

Review 1. Infections in cancer patients.

2. Studies in chronic allergic bronchopulmonary aspergillosis. 1. Clinical and physiological findings.

Review 3. Chronic granulomatous disease.

4. Disorders of candidacidal activity and other neutrophil functions in three cases of chronic candidiasis.

5. Intracellular bactericidal activity of leukocytes in whole blood for the diagnosis of chronic granulomatous disease of childhood.

Review 6. Hematologic malignancies and other marrow failure states: progress in the management of complicating infections.

7. Leukocyte myeloperoxidase deficiency and disseminated candidiasis: the role of myeloperoxidase in resistance to Candida infection.

8. Defective Aspergillus killing by neutrophil leucocytes in a case of systemic aspergillosis.

9. A genetic defect of granulocyte oxidative metabolism in a man with disseminated aspergillosis.

10. Disseminated aspergillosis treated with amphotericin B and surgery in a boy with chronic granulomatous disease.

Review 1. Host-parasite interaction in fungal infections.

2. Hematogenously acquired Aspergillus vertebral osteomyelitis in seemingly immunocompetent drug addicts.

Review 3. Aspergillus fumigatus and aspergillosis.

Review 4. Aspergillosis.