Literature DB >> 6367741

A cell division-active protein from E. coli.

A Caprioli, G Donelli, V Falbo, R Possenti, L G Roda, G Roscetti, F M Ruggeri.   

Abstract

A purification procedure for a protein obtained from an pathogenic strain of E. coli is described. The protein-called CNF-is active in inhibiting the duplication of cultured mammalian cells. Since nuclei division is apparently normal, treatment of cultured cells with CNF leads to the formation of gigantic, polynucleated cells. The purified protein is chromatographically and electrophoretically homogeneous. A partial characterization of CNF protein is also given.

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Year:  1984        PMID： 6367741     DOI： 10.1016/0006-291x(84)91343-3

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  28 in total

1.  Production of cytotoxic necrotizing factor, verocytotoxin and haemolysin by pyelonephritogenic Escherichia coli.

Authors:  A Brauner; M Katouli; K Tullus; S H Jacobson
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1990-10       Impact factor: 3.267

2.  Cytotoxic necrotizing factor type 1 of uropathogenic Escherichia coli kills cultured human uroepithelial 5637 cells by an apoptotic mechanism.

Authors:  M Mills; K C Meysick; A D O'Brien
Journal:  Infect Immun       Date:  2000-10       Impact factor: 3.441

3.  Gene block encoding production of cytotoxic necrotizing factor 1 and hemolysin in Escherichia coli isolates from extraintestinal infections.

Authors:  V Falbo; M Famiglietti; A Caprioli
Journal:  Infect Immun       Date:  1992-06       Impact factor: 3.441

4.  Isolation and nucleotide sequence of the gene encoding cytotoxic necrotizing factor 1 of Escherichia coli.

Authors:  V Falbo; T Pace; L Picci; E Pizzi; A Caprioli
Journal:  Infect Immun       Date:  1993-11       Impact factor: 3.441

5.  Cytotoxic necrotizing factor production by hemolytic strains of Escherichia coli causing extraintestinal infections.

Authors:  A Caprioli; V Falbo; F M Ruggeri; L Baldassarri; R Bisicchia; G Ippolito; E Romoli; G Donelli
Journal:  J Clin Microbiol       Date:  1987-01       Impact factor: 5.948

6.  Immunochemical identification and biological characterization of cytotoxic necrotizing factor from Escherichia coli.

Authors:  J De Rycke; L Phan-Thanh; S Bernard
Journal:  J Clin Microbiol       Date:  1989-05       Impact factor: 5.948

7.  Pasteurella multocida toxin is a mitogen for bone cells in primary culture.

Authors:  P B Mullan; A J Lax
Journal:  Infect Immun       Date:  1996-03       Impact factor: 3.441

8.  Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin stress fibers.

Authors:  E Oswald; M Sugai; A Labigne; H C Wu; C Fiorentini; P Boquet; A D O'Brien
Journal:  Proc Natl Acad Sci U S A       Date:  1994-04-26       Impact factor: 11.205

9.  Toxin production and haemagglutination in strains of Escherichia coli from diarrhoea in Brescia, Italy.

Authors:  R Bisicchia; R Ciammarughi; A Caprioli; V Falbo; F M Ruggeri
Journal:  J Hyg (Lond)       Date:  1985-10

10.  Hemolysin of uropathogenic Escherichia coli evokes extensive shedding of the uroepithelium and hemorrhage in bladder tissue within the first 24 hours after intraurethral inoculation of mice.

Authors:  Yarery C Smith; Susan B Rasmussen; Kerian K Grande; Richard M Conran; Alison D O'Brien
Journal:  Infect Immun       Date:  2008-04-28       Impact factor: 3.441
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