Signet ring cell lymphoma. A report of a case and review of the literature.

A case of signet ring cell lymphoma, a rare variant of follicular center cell lymphoma, is presented with a review of 20 other such lymphomas previously reported in the English literature. The histologic, immunocytologic, and electron microscopic features are described with speculation as to the possible relationship of this lymphoma to other B-lymphocyte-derived neoplasms.