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Literature DB >> 636668

The relationship between polymorphonuclear granulocytes and cartilage destruction in rheumatoid arthritis.

Abstract

The pannus-cartilage junction was investigated in cases of rheumatoid joint destruction. By a histochemical method for demonstrating the presence of neutrophil granulocytes, it became obvious that these cells in some cases were found in high numbers in the immediate vicinity of the cartilage in the process of being destroyed. It is concluded that these blood-carried cells may also participate in cartilage destruction in acute phases of chronic rheumatoid disease.

Entities: Disease

Mesh：

Year: 1978 PMID： 636668

Source DB: PubMed Journal: Z Rheumatol ISSN： 0340-1855 Impact factor: 1.372

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Cited

12 in total

1. Chondrocyte-derived cells and matrix at the rheumatoid cartilage-pannus junction identified with monoclonal antibodies.

Authors: S A Allard; K D Muirden; K L Camplejohn; R N Maini
Journal: Rheumatol Int Date: 1987 Impact factor: 2.631

2. Polymorphonuclear granulocytes in rheumatic tissue destruction. VI. The occurrence of PMNs in menisci of patients with rheumatoid arthritis.

Authors: W Mohr; B Pelster; D Wessinghage
Journal: Rheumatol Int Date: 1984 Impact factor: 2.631

3. Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production.

Authors: Henrique P Lemos; Renata Grespan; Silvio M Vieira; Thiago M Cunha; Waldiceu A Verri; Karla S S Fernandes; Fabricio O Souto; Iain B McInnes; Sergio H Ferreira; Foo Y Liew; Fernando Q Cunha
Journal: Proc Natl Acad Sci U S A Date: 2009-03-16 Impact factor: 11.205

4. Mast cells at sites of cartilage erosion in the rheumatoid joint.

Authors: M Bromley; W D Fisher; D E Woolley
Journal: Ann Rheum Dis Date: 1984-02 Impact factor: 19.103

5. Degradation in vivo of articular cartilage in rheumatoid arthritis by leucocyte elastase from polymorphonuclear leucocytes.

Authors: M Velvart; K Fehr; A Baici; G Sommermeyer; M Knöpfel; M Cancer; P Salgam; A Böni
Journal: Rheumatol Int Date: 1981 Impact factor: 2.631

Review 6. Lysosomal elastase: effect on mechanical and biochemical properties of normal cartilage, inhibition by polysulfonated glycosaminoglycan, and binding to chondrocytes.

Authors: H Menninger; H Burkhardt; W Röske; W Ehlebracht; B Hering; E Gurr; W Mohr; H D Mierau
Journal: Rheumatol Int Date: 1981 Impact factor: 2.631

The relationship between polymorphonuclear granulocytes and cartilage destruction in rheumatoid arthritis.

1. Chondrocyte-derived cells and matrix at the rheumatoid cartilage-pannus junction identified with monoclonal antibodies.

2. Polymorphonuclear granulocytes in rheumatic tissue destruction. VI. The occurrence of PMNs in menisci of patients with rheumatoid arthritis.

3. Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production.

4. Mast cells at sites of cartilage erosion in the rheumatoid joint.

5. Degradation in vivo of articular cartilage in rheumatoid arthritis by leucocyte elastase from polymorphonuclear leucocytes.

Review 6. Lysosomal elastase: effect on mechanical and biochemical properties of normal cartilage, inhibition by polysulfonated glycosaminoglycan, and binding to chondrocytes.

7. The inactivation of the polymorphonuclear leukocyte by non-steroidal anti-inflammatory drugs.

8. Cartilage degradation by polymorphonuclear leucocytes: in vitro assessment of the pathogenic mechanisms.

9. Role of polymorphs in inflammatory cartilage destruction in adjuvant arthritis of rats.

Review 10. Role of neutrophils in systemic autoimmune diseases.