| Literature DB >> 6365987 |
J D Bos, J H Sillevis Smitt, S R Krieg, P M Bakker, G D Vos, D J van Zaane.
Abstract
The proliferating skin cells in a case of acute disseminated histiocytosis-X (Abt-Letterer-Siwe disease) confirmed by electron microscopy, were characterized by a panel of monoclonal antibodies using an immunoperoxidase technique. The "histiocytes" were found to stain with OKT-6 (anti-T6) and anti-HLA-DR antibodies. Unexpectedly, slight staining was also observed with Leu 3a (anti-T4) and OKM-1. A proliferative process of T4, T6, HLA-DR, OKM-1 positive Langerhans' cells has not yet been described and may be specific for histiocytosis-X.Mesh:
Substances:
Year: 1984 PMID: 6365987 DOI: 10.1111/j.1600-0560.1984.tb00350.x
Source DB: PubMed Journal: J Cutan Pathol ISSN: 0303-6987 Impact factor: 1.587