| Literature DB >> 6365735 |
Y K Sun, Y P Xi, C M Fenoglio, N Pushparaj, K M O'Toole, G S Kledizik, E G Nette, D W King.
Abstract
The results of a combined immunocytochemical, morphometric, and clinicopathologic analysis of growth-hormone-producing and prolactin-producing pituitary cells in 28 subjects ranging in age from 16 to 90 are reported. There was a significant age-related decline in the number and size of growth-hormone-producing cells, which was most marked in the transition from youth to middle age. There was also a significant age-related decline in the number of pituitary parenchymal cells but not in pituitary weight. Prolactin cells did not show a significant decline in number with age.Entities:
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Year: 1984 PMID： 6365735 DOI： 10.1016/s0046-8177(84)80058-1
Source DB: PubMed Journal: Hum Pathol ISSN： 0046-8177 Impact factor: 3.466