Literature DB >> 6365584

Participation of microtubules and microfilaments in the transcellular biliary secretion of immunoglobulin A in primary cultures of rat hepatocytes.

R Gebhardt.   

Abstract

The biliary secretion of immunoglobulin A (IgA) in primary hepatocyte cultures was investigated by means of immunofluorescence. The characteristic accumulation of IgA in visible bile canaliculi was found to be strongly inhibited by vinblastine and colchicine or by cytochalasin B, but its surface binding was not.

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Year:  1984        PMID： 6365584     DOI： 10.1007/bf01947576

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  19 in total

1.  Microfilament dysfunction as a possible cause of intrahepatic cholestasis.

Authors:  M J Phillips; M Oda; E Mak; M M Fisher; K N Jeejeebhoy
Journal:  Gastroenterology       Date:  1975-07       Impact factor: 22.682

2.  Mechanism of secretion of biliary lipids: role of a microtubular system in hepatocellular transport of biliary lipids in the rat.

Authors:  D H Gregory; Z R Vlahcevic; M F Prugh; L Swell
Journal:  Gastroenterology       Date:  1978-01       Impact factor: 22.682

3.  Evidence for a role of the microtubular system in the secretion of newly synthesized albumin and other proteins by the liver.

Authors:  Y Le Marchand; C Patzelt; F Assimacopoulos-Jeannet; E G Loten; B Jeanrenaud
Journal:  J Clin Invest       Date:  1974-06       Impact factor: 14.808

4.  Interaction of drugs with microtubule proteins.

Authors:  L Wilson; J R Bamburg; S B Mizel; L M Grisham; K M Creswell
Journal:  Fed Proc       Date:  1974-02

5.  Primary cultures of rat hepatocytes as a model system of canalicular development, biliary secretion, and intrahepatic cholestasis. I. Distribution of filipin-cholesterol complexes during de novo formation of bile canaliculi.

Authors:  R Gebhardt; W Jung; H Robenek
Journal:  Eur J Cell Biol       Date:  1982-11       Impact factor: 4.492

6.  Alterations in activity and ultrastructural localization of several phosphatases on the surface of adult rat hepatocytes in primary monolayer culture.

Authors:  W Jung; R Gebhardt; D Mecke
Journal:  Eur J Cell Biol       Date:  1982-06       Impact factor: 4.492

7.  Inhibition by colchicine of fibrinogen translocation in hepatocytes.

Authors:  G Feldmann; M Maurice; C Sapin; J P Benhamou
Journal:  J Cell Biol       Date:  1975-10       Impact factor: 10.539

8.  Biliary secretion of sodium fluorescein in primary monolayer cultures of adult rat hepatocytes and its stimulation by nicotinamide.

Authors:  R Gebhardt; W Jung
Journal:  J Cell Sci       Date:  1982-08       Impact factor: 5.285

9.  Identification of secretory component as an IgA receptor on rat hepatocytes.

Authors:  D J Socken; K N Jeejeebhoy; H Bazin; B J Underdown
Journal:  J Exp Med       Date:  1979-12-01       Impact factor: 14.307

10.  Secretory component as the receptor for polymeric IgA on rat hepatocytes.

Authors:  E Orlans; J Peppard; J F Fry; R H Hinton; B M Mullock
Journal:  J Exp Med       Date:  1979-12-01       Impact factor: 14.307
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  2 in total

1.  Changes in the organization and antigenic determinants of intermediate filaments of rat hepatocytes after infusion of cytochalasin B in vivo.

Authors:  M Ohta; N Marceau; S W French
Journal:  Am J Pathol       Date:  1988-12       Impact factor: 4.307

2.  Investigation of endosomal compartments involved in endocytosis and transcytosis of polymeric immunoglobulin A by subcellular fractionation of perfused isolated rat liver.

Authors:  J H Perez; W J Branch; L Smith; B M Mullock; J P Luzio
Journal:  Biochem J       Date:  1988-05-01       Impact factor: 3.857
  2 in total

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