Literature DB >> 6365423

Antioxidant-stabilized amphotericin B.

W H Beggs.   

Abstract

A review of several recent reports shows that many compounds possessing antioxidant or mild reducing properties can enhance the bioactivity of amphotericin B. Antioxidants apparently retard autoxidative inactivation of this primary antifungal antibiotic. Stabilization of amphotericin B in this manner might have practical applications. Some important possibilities are identified and discussed.

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Year:  1983        PMID: 6365423     DOI: 10.1016/0732-8893(83)90011-1

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN: 0732-8893            Impact factor:   2.803


  3 in total

1.  Comparative tissue distribution and elimination of amphotericin B colloidal dispersion (Amphocil) and Fungizone after repeated dosing in rats.

Authors:  L H Wang; R M Fielding; P C Smith; L S Guo
Journal:  Pharm Res       Date:  1995-02       Impact factor: 4.200

2.  Chemosensitization as a means to augment commercial antifungal agents.

Authors:  Bruce C Campbell; Kathleen L Chan; Jong H Kim
Journal:  Front Microbiol       Date:  2012-02-29       Impact factor: 5.640

3.  Influence of ascorbic acid and α-tocopherol on the autoxidation and in vitro antifungal activity of amphotericin B.

Authors:  Mohammed Habib Belhachemi; Zahia Boucherit-Otmani; Kebir Boucherit; Sara Belmir
Journal:  Curr Med Mycol       Date:  2021-03
  3 in total

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