Literature DB >> 6365096

Separation of cytidine diphosphate reductase from rat Yoshida ascites sarcoma.

T Morita, J Murayama, N Shimizu, Y Moriyama, S Fujimura.   

Abstract

CDP reductase was separated from the cytosol of rat Yoshida ascites sarcoma. The precipitate, which resulted from the acidification of the cytosol by acetic acid at pH 5.2, catalyzed specifically the reduction of CDP, whereas the concurrently resulted supernatant catalyzed those of UDP, ADP and GDP. The CDP reductase showed a single peak in the pattern of the enzyme activity in DEAE-cellulose and also in Sepharose 4B column chromatography with adequate recovery of the activity.

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Year:  1984        PMID: 6365096     DOI: 10.1016/0006-291x(84)91088-x

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  1 in total

1.  Imbalance of deoxyribonucleoside triphosphates and DNA double-strand breaks in mouse mammary tumor FM3A cells treated in vitro with an antineoplastic tropolone derivative.

Authors:  M Yamato; Y Hirota; S Yoshida; S Tanaka; T Morita; J Sakai; K Hashigaki; H Hayatsu; Y Wataya
Journal:  Jpn J Cancer Res       Date:  1992-06
  1 in total

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