Major complications of marrow harvesting for transplantation.

Complications to bone marrow donors were analyzed for 2027 transplants reported to the International Bone Marrow Transplant Registry and for 1263 transplants performed in Seattle. Thus, a total of 3290 donor risk episodes were available for study. The incidence of major, i.e., life-threatening complications in the combined series was 0.27%. Neither death nor permanent residua occurred in any of the donors.