| Literature DB >> 6362074 |
S B Baloda, A Faris, K Krovacek, T Wadström.
Abstract
Strains of Salmonella enteritidis and Salmonella typhimurium isolated from human diarrheal cases produced heat-labile enterotoxin(s) and cytotoxic factor(s) which elongated, lysed or deformed Chinese hamster ovary cells in tissue culture. The toxin(s) caused fluid accumulation in ligated rabbit gut loops and produced increased skin permeability. Salmonella toxin produced by these strains does not cross-react immunologically with high titer Vibrio cholerae toxin antisera or heat-labile Escherichia coli enterotoxin antisera used in this study and does not bind to galactose--Sepharose gel. The activity of the toxin was not inhibited by GM1-ganglioside.Entities:
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Year: 1983 PMID： 6362074 DOI： 10.1016/0041-0101(83)90067-3
Source DB: PubMed Journal: Toxicon ISSN： 0041-0101 Impact factor: 3.033