Literature DB >> 6361036

Surgical treatment of giant-cell tumor of the spine. The experience at the Istituto Ortopedico Rizzoli.

R Savini, F Gherlinzoni, M Morandi, J R Neff, P Picci.   

Abstract

We reviewed the cases of nine patients with a giant-cell tumor of the vertebrae. All segments of the spine can be affected by the tumor, but there was a predilection for the lumbar segments in our series. Pain was present in all patients. The maximum duration before the diagnosis was made was three years and the minimum, forty-five days (average, 12.2 months). In six patients a neural deficit was also present. One patient was treated many years ago by radiation therapy alone; three patients were treated by decompressive laminectomy; two, by excision of the lesion and postoperative radiation therapy; and three patients underwent lesional but extensive excision as well as arthrodesis without any preoperative or postoperative radiation therapy. We have obtained good results with the latter treatment; after follow-ups of sixty, twenty-six, and twenty-four months in three patients the pain and the neural symptoms subsided, while roentgenographic examination showed no evidence of local recurrence. In all patients the autogenous bone grafts appeared to be incorporated, without any secondary deformity. We concluded that, due to the development of better surgical techniques, the surgical approach is probably the best modern treatment for a giant-cell tumor located in the spine.

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Year:  1983        PMID: 6361036

Source DB:  PubMed          Journal:  J Bone Joint Surg Am        ISSN: 0021-9355            Impact factor:   5.284


  15 in total

1.  Giant cell tumor of the fifth lumbar vertebra with a three-year follow-up: case report and review of the literature.

Authors:  Michael Athanassacopoulos; Georgios K Triantafyllopoulos; Spyridon G Pneumaticos
Journal:  Eur J Orthop Surg Traumatol       Date:  2012-03-25

2.  Bilateral Hydronephrosis Secondary to Giant Cell Tumor of the Sacrum.

Authors:  Omer Farooq Rehman; Amer K Hussain; Mohammad Ummair; Musab Umair; Muhammad Waqar
Journal:  Cureus       Date:  2020-12-15

Review 3.  Giant cell tumor of the sacrum and spine: series of 23 cases and a review of the literature.

Authors:  Christopher Martin; Edward F McCarthy
Journal:  Iowa Orthop J       Date:  2010

4.  Treatment and outcome of primary aggressive giant cell tumor in the spine.

Authors:  Huabin Yin; Xinghai Yang; Wei Xu; Binbin Li; Bo Li; Ting Wang; Tong Meng; Peng Wang; Tielong Liu; Wang Zhou; Jianru Xiao
Journal:  Eur Spine J       Date:  2015-01-29       Impact factor: 3.134

Review 5.  Tumors of the osseous spine.

Authors:  Narayan Sundaresan; Stephano Boriani; Allen Rothman; Robert Holtzman
Journal:  J Neurooncol       Date:  2004 Aug-Sep       Impact factor: 4.130

6.  Extended posterior circumferential approach to thoracic and thoracolumbar spine.

Authors:  Gabriel D Sundararaj; Krishnan Venkatesh; Parasa Narendra Babu; Rohit Amritanand
Journal:  Oper Orthop Traumatol       Date:  2009-09       Impact factor: 1.154

7.  Giant cell tumor of the spine: A review of 9 surgical interventions in 6 cases.

Authors:  Shekhar Y Bhojraj; Abhay Nene; Sheetal Mohite; Raghuprasad Varma
Journal:  Indian J Orthop       Date:  2007-04       Impact factor: 1.251

8.  Total en bloc lumbar spondylectomy of follicular thyroid carcinoma.

Authors:  Dae-Jean Jo; Jae-Kyun Jun; Sung-Min Kim
Journal:  J Korean Neurosurg Soc       Date:  2009-03-31

9.  Clinical Outcome of Treatment for Patients with Giant Cell Tumor in Spine.

Authors:  Seon Chun Kim; Wonik Cho; Ung-Kyu Chang; Sang Min Youn
Journal:  J Korean Neurosurg Soc       Date:  2015-09-30

10.  Role of Bisphosphonates as Adjuvants of Surgery in Giant Cell Tumor of Spine.

Authors:  Chaitanya Dev Pannu; Pankaj Kandhwal; Vijay Raghavan; Shah Alam Khan; Shishir Rastogi; Arvind Jayaswal
Journal:  Int J Spine Surg       Date:  2018-12-21
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