Literature DB >> 6360818

A study of the fibrin plate assay of fibrinolytic agents. Optimal conditions, reproducibility and precision.

J Jespersen, T Astrup.   

Abstract

The reproducibility, precision and required conditions of the fibrin plate method for determination of fibrinolytic agents are described in detail. Under optimal conditions the assay is a sensitive and precise method for the quantitative determination of fibrinolytic agents. Thus, with a tissue plasminogen activator preparation its sensitivity is approximately 0.02 CTA urokinase units/ml, and dilutions yielded a curve with a slope (double-logarithmic) with a day-to-day mean of 0.53 with a coefficient of variation of 5.1%.

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Year:  1983        PMID： 6360818     DOI： 10.1159/000214769

Source DB:  PubMed          Journal:  Haemostasis        ISSN： 0301-0147


  9 in total

1.  Reprogrammed streptokinases develop fibrin-targeting and dissolve blood clots with more potency than tissue plasminogen activator.

Authors:  I Y Sazonova; R A McNamee; A K Houng; S M King; L Hedstrom; G L Reed
Journal:  J Thromb Haemost       Date:  2009-06-30       Impact factor: 5.824

2.  Adenovirus-mediated urokinase gene transfer induces liver regeneration and allows for efficient retrovirus transduction of hepatocytes in vivo.

Authors:  A Lieber; M J Vrancken Peeters; L Meuse; N Fausto; J Perkins; M A Kay
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-20       Impact factor: 11.205

3.  Losac, the first hemolin that exhibits procogulant activity through selective factor X proteolytic activation.

Authors:  Miryam Paola Alvarez-Flores; Daniel Furlin; Oscar H P Ramos; Andrea Balan; Katsuhiro Konno; Ana Marisa Chudzinski-Tavassi
Journal:  J Biol Chem       Date:  2010-12-22       Impact factor: 5.157

4.  [Successful treatment of superior mesenteric artery thrombosis with local high-dose urokinase therapy].

Authors:  M Köhler; B Kramann; P Hellstern; W Fess; P Walter; H Woerner; R Kiehl; E Wenzel
Journal:  Klin Wochenschr       Date:  1985-08-01

5.  A prothrombin activator from Bothrops erythromelas (jararaca-da-seca) snake venom: characterization and molecular cloning.

Authors:  Márcia B Silva; Mirta Schattner; Celso R R Ramos; Inácio L M Junqueira-de-Azevedo; Míriam C Guarnieri; María A Lazzari; Claudio A M Sampaio; Roberto G Pozner; Janaina S Ventura; Paulo L Ho; Ana M Chudzinski-Tavassi
Journal:  Biochem J       Date:  2003-01-01       Impact factor: 3.857

6.  Functional variability of snake venom metalloproteinases: adaptive advantages in targeting different prey and implications for human envenomation.

Authors:  Juliana L Bernardoni; Leijiane F Sousa; Luciana S Wermelinger; Aline S Lopes; Benedito C Prezoto; Solange M T Serrano; Russolina B Zingali; Ana M Moura-da-Silva
Journal:  PLoS One       Date:  2014-10-14       Impact factor: 3.240

7.  Effects of 6 Months of Active Commuting and Leisure-Time Exercise on Fibrin Turnover in Sedentary Individuals with Overweight and Obesity: A Randomised Controlled Trial.

Authors:  Anne Sofie Gram; Martin Bæk Petersen; Jonas Salling Quist; Mads Rosenkilde; Bente Stallknecht; Else-Marie Bladbjerg
Journal:  J Obes       Date:  2018-05-16

Review 8.  Development and Testing of Thrombolytics in Stroke.

Authors:  Dmitri Nikitin; Seungbum Choi; Jan Mican; Martin Toul; Wi-Sun Ryu; Jiri Damborsky; Robert Mikulik; Dong-Eog Kim
Journal:  J Stroke       Date:  2021-01-31       Impact factor: 6.967

9.  Insights into the Mechanisms Involved in Strong Hemorrhage and Dermonecrosis Induced by Atroxlysin-Ia, a PI-Class Snake Venom Metalloproteinase.

Authors:  Luciana Aparecida Freitas-de-Sousa; Mônica Colombini; Mônica Lopes-Ferreira; Solange M T Serrano; Ana Maria Moura-da-Silva
Journal:  Toxins (Basel)       Date:  2017-08-02       Impact factor: 4.546
  9 in total

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