Literature DB >> 6360252

Bone marrow cell dose and kinetics of recovery following allogeneic marrow transplantation in man.

D Niederwieser, A Gratwohl, M Oberholzer, B Osterwalder, C Nissen, B Speck.   

Abstract

In 50 patients transplanted for acute or chronic leukemia we studied the correlation between the number of infused bone marrow cells/kg recipient body weight and the time needed for engraftment. Engraftment was arbitrarily defined as the first day of 1 X 10(9) leukocytes/l and of 20 X 10(9) reticulocytes/l after the posttransplantation nadir. There is a negative non-linear correlation between the duration of leukopenia following marrow transplantation and the amount of transfused nucleated cells (p = 0.01). Since the incidence of infectious or hemorrhagic complications depends directly on the duration of aplasia it is justifiable to give a maximal cell dose.

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Mesh：

Year:  1983        PMID： 6360252     DOI： 10.1007/bf00320350

Source DB:  PubMed          Journal:  Blut        ISSN： 0006-5242


  13 in total

1.  Marrow transplants in lethally irradiated dogs given methotrexate.

Authors:  E D THOMAS; J A COLLINS; E C HERMAN; J W FERREBEE
Journal:  Blood       Date:  1962-02       Impact factor: 22.113

2.  The effect of the amount of isologous bone marrow injected on the recovery of hematopoietic organs, survival and body weight after lethal irradiation injury in mice.

Authors:  P URSO; C C CONGDON
Journal:  Blood       Date:  1957-03       Impact factor: 22.113

3.  Preservation of radiation recovery factor in frozen marrow.

Authors:  J W FERREBEE; D BILLEN; I M URSO; W C LU; E D THOMAS; C C CONGDON
Journal:  Blood       Date:  1957-12       Impact factor: 22.113

Review 4.  Bone-marrow transplantation (first of two parts).

Authors:  E Thomas; R Storb; R A Clift; A Fefer; F L Johnson; P E Neiman; K G Lerner; H Glucksberg; C D Buckner
Journal:  N Engl J Med       Date:  1975-04-17       Impact factor: 91.245

Review 5.  Bone marrow transplantation in leukaemia (review).

Authors:  B Speck
Journal:  Anticancer Res       Date:  1981       Impact factor: 2.480

6.  Fractionated total body irradiation and autologous bone marrow transplantation in dogs: hemopoietic recovery after various marrow cell doses.

Authors:  U Bodenberger; H J Kolb; I Rieder; B Netzel; E Schäffer; H Kolb; S Thierfelder
Journal:  Exp Hematol       Date:  1980-04       Impact factor: 3.084

7.  [Treatment of severe aplastic anemia].

Authors:  A Gratwohl; B Osterwalder; C Nissen; U Leibundgut; E Signer; A Lüthy; M Jeannet; B Speck
Journal:  Schweiz Med Wochenschr       Date:  1981-10-10

Review 8.  Aplastic anemia (first of two parts): pathogenesis, diagnosis, treatment, and prognosis.

Authors:  B M Camitta; R Storb; E D Thomas
Journal:  N Engl J Med       Date:  1982-03-18       Impact factor: 91.245

9.  [Graft versus host disease, a little known complication of blood transfusion].

Authors:  P Groff; J Torhorst; B Speck; C Nissen; W Weber; P Cornu; J Rossier; L Biland
Journal:  Schweiz Med Wochenschr       Date:  1976-05

10.  Constant post-irradiation repopulation rates and linear relationship between cellular blood response and number of transplanted bone marrow cells in inbred mice.

Authors:  B H Petersen
Journal:  Scand J Haematol       Date:  1977-03
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  3 in total

1.  Early reconstitution of haematopoiesis after allogeneic bone marrow transplantation: a prospective histopathological study of bone marrow biopsy specimens.

Authors:  H van den Berg; P M Kluin; J M Vossen
Journal:  J Clin Pathol       Date:  1990-05       Impact factor: 3.411

2.  Immunoadsorption for removal of anti-A and anti-B blood group antibodies in ABO-incompatible bone marrow transplantation.

Authors:  B Osterwalder; A Gratwohl; C Nissen; B Speck
Journal:  Blut       Date:  1986-11

3.  Acute folic acid deficiency after bone marrow transplantation.

Authors:  H Link; M Blaurock; P Wernet; D Niethammer; K Wilms; P Ostendorf
Journal:  Klin Wochenschr       Date:  1986-05-02
  3 in total

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